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Journal of Zhejiang University SCIENCE B 2005 Vol.6 No.11 P.1063-1068


Dependence of the E. coli promoter strength and physical parameters upon the nucleotide sequence

Author(s):  BEREZHNOY Andrey Y., SHCKORBATOV Yuriy G.

Affiliation(s):  National Scientific Center, Kharkov Physical-Technical Institute, Kharkov 61108, Ukraine; more

Corresponding email(s):   Yury.G.Shckorbatov@univer.kharkov.ua

Key Words:  DNA sequence, Promoter strength, Nucleotide pair energy, &minus, 35 sequence, &minus, 10 sequence, +7 sequence

BEREZHNOY Andrey Y., SHCKORBATOV Yuriy G.. Dependence of the E. coli promoter strength and physical parameters upon the nucleotide sequence[J]. Journal of Zhejiang University Science B, 2005, 6(11): 1063-1068.

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T1 - Dependence of the E. coli promoter strength and physical parameters upon the nucleotide sequence
A1 - BEREZHNOY Andrey Y.
J0 - Journal of Zhejiang University Science B
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SP - 1063
EP - 1068
%@ 1673-1581
Y1 - 2005
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2005.B1063

The energy of interaction between complementary nucleotides in promoter sequences of E. coli was calculated and visualized. The graphic method for presentation of energy properties of promoter sequences was elaborated on. Data obtained indicated that energy distribution through the length of promoter sequence results in picture with minima at –35, –8 and +7 regions corresponding to areas with elevated AT (adenine-thymine) content. The most important difference from the random sequences area is related to –8. Four promoter groups and their energy properties were revealed. The promoters with minimal and maximal energy of interaction between complementary nucleotides have low strengths, the strongest promoters correspond to promoter clusters characterized by intermediate energy values.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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kannadasan@Manonmaniam Sudaranar University<Kannagenes@gmail.com>

2013-04-28 14:13:31

Hi My Name is Kannadasan Working in small biotech company as Scientific Assistant. Im looking for E. coli promoters. I found your page. Hope I will be helped by this Paper.

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