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Received: 2006-01-16

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Journal of Zhejiang University SCIENCE B 2007 Vol.8 No.2 P.116-120


Evaluation of organ distribution of microcystins in the freshwater phytoplanktivorous fish Hypophthalmichthys molitrix

Author(s):  ZHANG Hang-jun, ZHANG Jian-ying, HONG Ye, CHEN Ying-xu

Affiliation(s):  School of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310028, China

Corresponding email(s):   zjy@zju.edu.cn

Key Words:  Microcystin, Organ distribution, Bioaccumulation, Fish, Risk

ZHANG Hang-jun, ZHANG Jian-ying, HONG Ye, CHEN Ying-xu. Evaluation of organ distribution of microcystins in the freshwater phytoplanktivorous fish Hypophthalmichthys molitrix[J]. Journal of Zhejiang University Science B, 2007, 8(2): 116-120.

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author="ZHANG Hang-jun, ZHANG Jian-ying, HONG Ye, CHEN Ying-xu",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

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%A ZHANG Hang-jun
%A ZHANG Jian-ying
%A CHEN Ying-xu
%J Journal of Zhejiang University SCIENCE B
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%P 116-120
%@ 1673-1581
%D 2007
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2007.B0116

T1 - Evaluation of organ distribution of microcystins in the freshwater phytoplanktivorous fish Hypophthalmichthys molitrix
A1 - ZHANG Hang-jun
A1 - ZHANG Jian-ying
A1 - HONG Ye
A1 - CHEN Ying-xu
J0 - Journal of Zhejiang University Science B
VL - 8
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EP - 120
%@ 1673-1581
Y1 - 2007
PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.2007.B0116

To evaluate the public health risk of exposure to microcystins in fish food in China, the distribution pattern of microcystin-LR and microcystin-RR in various organs (liver, intestine, kidney, muscle and lipid) of the dominant freshwater phytoplanktivorous fish Hypophthalmichthys molitrix in Hangzhou, China’s Tiesha River was investigated with the method of HPLC-ESI-MS analysis. The distribution of microcystins was different in the fish organs and the major total microcystins (microcystin-LR and microcystin-RR) were present in the intestines (6.49 μg/g fresh weight), followed by the livers (4.52 μg/g fresh weight) and the muscles (2.86 μg/g fresh weight). microcystins were detected in kidneys (1.35 μg/g fresh weight), but not detected in lipid. The results suggested that the mean daily intake from fish was 0.03 μg/kg body weight which was very close to the recommended WHO tolerable daily intake (TDI) level of 0.04 μg/kg body weight per day, and local people were warned they may have health risk if they consumed fish from the river.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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