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Received: 2007-02-15

Revision Accepted: 2007-03-29

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Journal of Zhejiang University SCIENCE B 2007 Vol.8 No.6 P.435-438


Diagnosis and treatment of pheochromocytoma in urinary bladder

Author(s):  LIU Yong, DONG Sheng-guo, DONG Zhen, MAO Xin, SHI Xin-yan

Affiliation(s):  Department of Urology, Affiliated Hospital, School of Medicine, Qingdao University, Qingdao 266003, China

Corresponding email(s):   liuyong_0501@yahoo.com.cn

Key Words:  Urinary bladder, Pheochromocytoma, Diagnosis, Therapeutics

LIU Yong, DONG Sheng-guo, DONG Zhen, MAO Xin, SHI Xin-yan. Diagnosis and treatment of pheochromocytoma in urinary bladder[J]. Journal of Zhejiang University Science B, 2007, 8(6): 435-438.

@article{title="Diagnosis and treatment of pheochromocytoma in urinary bladder",
author="LIU Yong, DONG Sheng-guo, DONG Zhen, MAO Xin, SHI Xin-yan",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Diagnosis and treatment of pheochromocytoma in urinary bladder
%A LIU Yong
%A DONG Sheng-guo
%A DONG Zhen
%A MAO Xin
%A SHI Xin-yan
%J Journal of Zhejiang University SCIENCE B
%V 8
%N 6
%P 435-438
%@ 1673-1581
%D 2007
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2007.B0435

T1 - Diagnosis and treatment of pheochromocytoma in urinary bladder
A1 - LIU Yong
A1 - DONG Sheng-guo
A1 - DONG Zhen
A1 - MAO Xin
A1 - SHI Xin-yan
J0 - Journal of Zhejiang University Science B
VL - 8
IS - 6
SP - 435
EP - 438
%@ 1673-1581
Y1 - 2007
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2007.B0435

Objective: To study the diagnosis and treatment of pheochromocytoma in urinary bladder. Methods: Six cases of bladder pheochromocytoma were studied. Four cases showed hypertension, 3 of which were paroxysmal hypertension during urination. Catecholamine (CA) was increased in a case, and vanillymandelic acid (VMA) was increased in 2 cases. Bladder submucosal mass was detected by B-ultrasound in 5 cases (5/5), computerized tomography (CT) in 3 cases (3/3), cystoscopy in 5 cases (5/6). Four cases took α-receptor blocker for 2 weeks, 1 case took β-receptor blocker to decrease heart rate. All patients were treated with surgical operation including 4 partial cystectomies, 2 excavations. Results: Three cases had manifestations including headache, excessive perspiration and hypertension during cystoscopy. Four cases were confirmed before operation. Two cases showed hypertension during operation. All patients were pathologically diagnosed as pheochromocytoma postoperatively. In five cases followed up, blood pressure returned to normal. No patient had relapse and malignancy. Conclusions: Typical hypertension during urination comprised the main symptoms. We should highly suspect bladder pheochromocytoma if a submucosal mass was discovered with B-ultrasound, CT, 131I-MIBG (methyliodobenzylguanidine) and cystoscopy. The determination of CA in urine is valuable for qualitative diagnosis. The preoperative management of controlling blood pressure and expansion of the blood volume are very important. Surgical operation is a good method for effective treatment. Postoperative long-time followed up is necessary.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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