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Received: 2007-09-24

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Journal of Zhejiang University SCIENCE B 2007 Vol.8 No.12 P.885-887

http://doi.org/10.1631/jzus.2007.B0885


A case of chylothorax treated curatively with Sapylin, a streptococcus preparation


Author(s):  Xu Zhi-hao, Wang Chun-fu, Zhang Yue-qin, Shen Hua-hao, Xu Feng

Affiliation(s):  Department of Respiratory Diseases, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China

Corresponding email(s):   xufeng99@yahoo.com

Key Words:  Chylothorax, Sapylin, Streptococcus preparation


Xu Zhi-hao, Wang Chun-fu, Zhang Yue-qin, Shen Hua-hao, Xu Feng. A case of chylothorax treated curatively with Sapylin, a streptococcus preparation[J]. Journal of Zhejiang University Science B, 2007, 8(12): 885-887.

@article{title="A case of chylothorax treated curatively with Sapylin, a streptococcus preparation",
author="Xu Zhi-hao, Wang Chun-fu, Zhang Yue-qin, Shen Hua-hao, Xu Feng",
journal="Journal of Zhejiang University Science B",
volume="8",
number="12",
pages="885-887",
year="2007",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2007.B0885"
}

%0 Journal Article
%T A case of chylothorax treated curatively with Sapylin, a streptococcus preparation
%A Xu Zhi-hao
%A Wang Chun-fu
%A Zhang Yue-qin
%A Shen Hua-hao
%A Xu Feng
%J Journal of Zhejiang University SCIENCE B
%V 8
%N 12
%P 885-887
%@ 1673-1581
%D 2007
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2007.B0885

TY - JOUR
T1 - A case of chylothorax treated curatively with Sapylin, a streptococcus preparation
A1 - Xu Zhi-hao
A1 - Wang Chun-fu
A1 - Zhang Yue-qin
A1 - Shen Hua-hao
A1 - Xu Feng
J0 - Journal of Zhejiang University Science B
VL - 8
IS - 12
SP - 885
EP - 887
%@ 1673-1581
Y1 - 2007
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2007.B0885


Abstract: 
chylothorax is an uncommon disease where fatty fluid accumulates within the chest cavity. Conservative management, including repeated thoracentesis or pleurodesis, seems to be suitable to most cases. Herein, we present a case of efficacious pleurodesis by intrapleural injection of sapylin, a streptococcus preparation, for the treatment of chylothorax. A 52-year-old non-smoking female farmer was diagnosed as idiopathic chylothorax after we ruled out possible causes including chest trauma, lymphoma, lung cancer, filariasis, tuberculosis, and etc. Two-time intra-thoracic injection of 3 Klinische Einheit (KE) sapylin achieved rapid and effective control of chylothorax with no severe side effects. sapylin may facilitate pleurodesis by producing a strong inflammatory response.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference

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[7] Koga, K., Mita, Y., Dobashi, K., Masuo, T., Aihara, M., Shimizu, Y., Umegae, Y., Mori, M., 1999. Lung cancer with chylothorax successfully treated by chemical pleurodesis with OK-432. Nihon Kokyuki Gakkai Zasshi, 37(8):627-630 (in Japanese).

[8] Laranne, J., Keshi-Nisula, L., Rautio, R., Rautiainen, M., Airaksinen, M., 2002. OK-432 (Picibanil) therapy for lymphangiomas in children. Eur. Arch. Otorhinolaryngol., 259(5):274-278.

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