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Journal of Zhejiang University SCIENCE B 2008 Vol.9 No.6 P.496-499

http://doi.org/10.1631/jzus.B0720011


An insulinoma with clinical and electroencephalographic features resembling complex partial seizures


Author(s):  Shuang WANG, Hai-tao HU, Shu-qun WEN, Zhong-jin WANG, Bao-rong ZHANG, Mei-ping DING

Affiliation(s):  Department of Neurology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China

Corresponding email(s):   freud_wang@hotmail.com, dingmeiping@tom.com

Key Words:  Insulinoma, Hypoglycemia, Electroencephalography (EEG), Seizure


Shuang WANG, Hai-tao HU, Shu-qun WEN, Zhong-jin WANG, Bao-rong ZHANG, Mei-ping DING. An insulinoma with clinical and electroencephalographic features resembling complex partial seizures[J]. Journal of Zhejiang University Science B, 2008, 9(6): 496-499.

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author="Shuang WANG, Hai-tao HU, Shu-qun WEN, Zhong-jin WANG, Bao-rong ZHANG, Mei-ping DING",
journal="Journal of Zhejiang University Science B",
volume="9",
number="6",
pages="496-499",
year="2008",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B0720011"
}

%0 Journal Article
%T An insulinoma with clinical and electroencephalographic features resembling complex partial seizures
%A Shuang WANG
%A Hai-tao HU
%A Shu-qun WEN
%A Zhong-jin WANG
%A Bao-rong ZHANG
%A Mei-ping DING
%J Journal of Zhejiang University SCIENCE B
%V 9
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%P 496-499
%@ 1673-1581
%D 2008
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B0720011

TY - JOUR
T1 - An insulinoma with clinical and electroencephalographic features resembling complex partial seizures
A1 - Shuang WANG
A1 - Hai-tao HU
A1 - Shu-qun WEN
A1 - Zhong-jin WANG
A1 - Bao-rong ZHANG
A1 - Mei-ping DING
J0 - Journal of Zhejiang University Science B
VL - 9
IS - 6
SP - 496
EP - 499
%@ 1673-1581
Y1 - 2008
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B0720011


Abstract: 
We described a female patient with insulinoma who experienced recurrent episodes of automatism, confusion and convulsion. Furthermore, her electroencephalography (EEG) findings resembled the pattern in complex partial seizures with secondary generalization. The interictal EEG showed spikes and sharp waves, as well as focal slowing over the left temporal lobe, and the ictal EEG revealed generalized spikes and sharp waves associated with diffused slowing. She was initially misdiagnosed as pharmacoresistant epilepsy. After the insulinoma was found and surgically removed, her EEG turned normal and she was seizure-free during the 4-year follow-up. This report highlights the need for careful reassessment of all seizures refractory to medication, even for the patients associated with epileptiform discharges on EEG.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference

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