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CLC number: R135.1

On-line Access: 2011-03-09

Received: 2010-07-08

Revision Accepted: 2010-11-10

Crosschecked: 2011-01-26

Cited: 8

Clicked: 5537

Citations:  Bibtex RefMan EndNote GB/T7714

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Journal of Zhejiang University SCIENCE B 2011 Vol.12 No.3 P.189-192


Clinical features and treatment in patients with acute 2,4-dinitrophenol poisoning

Author(s):  Yuan-qiang Lu, Jiu-kun Jiang, Wei-dong Huang

Affiliation(s):  Department of Emergency, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China

Corresponding email(s):   luyuanqiang@yahoo.cn, huangweidong2003@hotmail.com

Key Words:  2, 4-Dinitrophenol, Poisoning, Therapeutics, Hemoperfusion, Glucocorticoid

Yuan-qiang Lu, Jiu-kun Jiang, Wei-dong Huang. Clinical features and treatment in patients with acute 2,4-dinitrophenol poisoning[J]. Journal of Zhejiang University Science B, 2011, 12(3): 189-192.

@article{title="Clinical features and treatment in patients with acute 2,4-dinitrophenol poisoning",
author="Yuan-qiang Lu, Jiu-kun Jiang, Wei-dong Huang",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Clinical features and treatment in patients with acute 2,4-dinitrophenol poisoning
%A Yuan-qiang Lu
%A Jiu-kun Jiang
%A Wei-dong Huang
%J Journal of Zhejiang University SCIENCE B
%V 12
%N 3
%P 189-192
%@ 1673-1581
%D 2011
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1000265

T1 - Clinical features and treatment in patients with acute 2,4-dinitrophenol poisoning
A1 - Yuan-qiang Lu
A1 - Jiu-kun Jiang
A1 - Wei-dong Huang
J0 - Journal of Zhejiang University Science B
VL - 12
IS - 3
SP - 189
EP - 192
%@ 1673-1581
Y1 - 2011
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1000265

Objective: To report clinical features and treatment of 16 cases of acute 2,4-Dinitrophenol poisoning. Methods: A total of 16 patients suffering from acute poisoning due to non-oral exposure to 2,4-Dinitrophenol were sent to our hospital. Two died within 3 h after admission, while the other 14 responded to supportive treatment and hemoperfusion. Clinical features and treatment of the patients were retrospectively analyzed and presented. Results: Fourteen patients recovered and were discharged after four to six weeks of treatment. No obvious poisoning sequelae were found in the three-month follow-up. Conclusions: Non-oral exposure to 2,4-Dinitrophenol is toxic. hemoperfusion and glucocorticoid treatments may be efficient measures to prevent mortality, but this requires further study.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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