CLC number: R57
On-line Access: 2024-08-27
Received: 2023-10-17
Revision Accepted: 2024-05-08
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Ling-ling JIANG, Bing-ling ZHANG, You-shi LIU. Is adult celiac disease really uncommon in Chinese?[J]. Journal of Zhejiang University Science B, 2009, 10(3): 168-171.
@article{title="Is adult celiac disease really uncommon in Chinese?",
author="Ling-ling JIANG, Bing-ling ZHANG, You-shi LIU",
journal="Journal of Zhejiang University Science B",
volume="10",
number="3",
pages="168-171",
year="2009",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B0820164"
}
%0 Journal Article
%T Is adult celiac disease really uncommon in Chinese?
%A Ling-ling JIANG
%A Bing-ling ZHANG
%A You-shi LIU
%J Journal of Zhejiang University SCIENCE B
%V 10
%N 3
%P 168-171
%@ 1673-1581
%D 2009
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B0820164
TY - JOUR
T1 - Is adult celiac disease really uncommon in Chinese?
A1 - Ling-ling JIANG
A1 - Bing-ling ZHANG
A1 - You-shi LIU
J0 - Journal of Zhejiang University Science B
VL - 10
IS - 3
SP - 168
EP - 171
%@ 1673-1581
Y1 - 2009
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B0820164
Abstract: celiac disease (CD) is a type of intestinal malabsorption syndrome, in which the patients are intolerant to the gliadin in dietary gluten, resulting in chronic diarrhea and secondary malnutrition. The disease is common in Europe and the United States, but only sporadic reports are found in East Asia including china. Is CD really rare in china? We examined 62 patients by capsule endoscopy for chronic diarrhea from June 2003 to March 2008. Four patients with chronic diarrhea and weight loss were diagnosed to have CD. Under the capsule endoscopy, we observed that the villi of the proximal small bowel became short, and that the mucous membrane became atrophied in these four patients. Duodenal biopsies were performed during gastroscopy and the pathological changes of mucosa were confirmed to be Marsh 3 stage of CD. A gluten free diet significantly improved the conditions of the four patients. We suspect that in china, especially in the northern area where wheat is the main food, CD might not be uncommon, and its under-diagnosis could be caused by its clinical manifestations that could be easily covered by the symptoms from other clinical situations, particularly when it came to subclinical patients without obvious symptom or to patients with extraintestinal symptoms as the initial manifestations.
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