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Journal of Zhejiang University SCIENCE B 2009 Vol.10 No.8 P.631-634


Takayasu’s arteritis associated with Crohn’s disease

Author(s):  You-shi LIU, You-hong FANG, Ling-xiang RUAN, You-ming LI, Lin LI, Ling-ling JIANG

Affiliation(s):  Department of Gastroenterology, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China; more

Corresponding email(s):   lys_2002cn@yahoo.com.cn, jll-03@hotmail.com

Key Words:  Takayasu&rsquo, s arteritis, Crohn&rsquo, s disease, Inflammatory bowel disease, Immune disorders

You-shi LIU, You-hong FANG, Ling-xiang RUAN, You-ming LI, Lin LI, Ling-ling JIANG. Takayasu’s arteritis associated with Crohn’s disease[J]. Journal of Zhejiang University Science B, 2009, 10(8): 631-634.

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author="You-shi LIU, You-hong FANG, Ling-xiang RUAN, You-ming LI, Lin LI, Ling-ling JIANG",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

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%T Takayasu’s arteritis associated with Crohn’s disease
%A You-shi LIU
%A You-hong FANG
%A Ling-xiang RUAN
%A You-ming LI
%A Lin LI
%A Ling-ling JIANG
%J Journal of Zhejiang University SCIENCE B
%V 10
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%P 631-634
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%D 2009
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B0820391

T1 - Takayasu’s arteritis associated with Crohn’s disease
A1 - You-shi LIU
A1 - You-hong FANG
A1 - Ling-xiang RUAN
A1 - You-ming LI
A1 - Lin LI
A1 - Ling-ling JIANG
J0 - Journal of Zhejiang University Science B
VL - 10
IS - 8
SP - 631
EP - 634
%@ 1673-1581
Y1 - 2009
PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.B0820391

takayasu&rsquo;s arteritis (TA), also known as the “pulseless disease,” is a chronic vasculitis of the aorta and aortic branches. TA with crohn&rsquo;s disease is rare and has not been documented in China before. In this paper we report on a case of takayasu&rsquo;s arteritis associated with concurrent crohn&rsquo;s disease. A 17-year-old Chinese male developed upper limb sourness and a sensation of fatigue, and his upper limb pulses were absent. He was diagnosed with TA and underwent an axillary artery bypass with autologous great saphenous vein on the left subclavian artery. After the surgery, he regained the normal blood pressure. This patient also had years of diarrhea and developed an anal canal ulcer, and was diagnosed with inflammatory bowel disease and ulcerative colitis before. Five months after the TA surgery, he was hospitalized for severe stomachache and diarrhea and was finally diagnosed with crohn&rsquo;s disease. The possible pathophysiological mechanisms responsible for concurrent existence of TA and crohn&rsquo;s disease may be associated with immune disorders, especially autoimmunity.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


[1] Akar, S., Can, G., Binicier, O., Aksu, K., Akinci, B., Solmaz, D., Birlik, M., Keser, G., Akkoc, N., Onen, F., 2008. Quality of life in patients with Takayasu’s arteritis is impaired and comparable with rheumatoid arthritis and ankylosing spondylitis patients. Clin. Rheumatol., 27(7): 859-865.

[2] Daryani, N.E., Habibi, A.N., Bashashati, M., Keramati, M.R., Rafiee, M.J., 2008. Takayasu’s arteritis associated with Crohn’s disease: a case report. J. Med. Case Rep., 2(1):87.

[3] Hokama, A., Kinjo, F., Arakaki, T., Matayoshi, R., Yonamine, Y., Tomiyama, R., Sunagawa, T., Makishi, T., Kawane, M., Koja, K., Saito, A., 2003. Pulseless hematochezia: Takayasu’s arteritis associated with ulcerative colitis. Intern. Med., 42(9):897-898.

[4] Ishikawa, K., 1978. Takayasu arteritis (occlusive thrombosortopathy)—etiological mechanism and classification. Nippon Rinsho, 36(4):808-814 (in Japanese).

[5] Levitsky, J., Harrison, J.R., Cohen, R.D., 2002. Crohn’s disease and Takayasu’s arteritis. J. Clin. Gastroenterol., 34(4):454-456.

[6] Rellecke, P., Strauer, B.E., 2006. Chronic inflammatory bowel disease and cardiovascular complications. Med. Klin. (Munich), 11:56-60.

[7] Reny, J.L., Paul, J.F., Lefebvre, C., 2003. Association of Takayasu’s arteritis and Crohn’s disease. Results of a study on 44 Takayasu patients and review of the literature. Ann. Med. Interne, 54:75-76.

[8] Sands, B.E., 2007. Inflammatory bowel disease: past, present, and future. J. Gastroenterol., 42(1):16-25.

[9] Tann, O.R., Tulloh, R.M., Hamilton, M.C., 2008. Takayasu’s disease: a review. Cardiol. Young, 18(3):250-259.

[10] Wang, A.G., Wang, J., Li, B., Tang, H.W., 2003. TA with SLE. One case report. Clin. J. Rheumatol., 7(5):319.

[11] Yassinger, S., Adelman, R., Cantor, D., Halsted, C.H., Bolt, R.J., 1976. Association of inflammatory bowel disease and large vascular lesions. Gastroenterology, 71(5): 844-846.

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