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Journal of Zhejiang University SCIENCE B 2009 Vol.10 No.4 P.258-263


Prebiotic oligosaccharides change the concentrations of short-chain fatty acids and the microbial population of mouse bowel

Author(s):  Xiao-dong PAN, Fen-qin CHEN, Tian-xing WU, Hong-gang TANG, Zhan-yu ZHAO

Affiliation(s):  Department of Chemistry, Zhejiang University, Hangzhou 310027, China; more

Corresponding email(s):   zjuwutianxing@hotmail.com

Key Words:  Oligosaccharides, Short-chain fatty acids (SCFAs), Bifidobacteria, Lactobacilli, Mouse

Xiao-dong PAN, Fen-qin CHEN, Tian-xing WU, Hong-gang TANG, Zhan-yu ZHAO. Prebiotic oligosaccharides change the concentrations of short-chain fatty acids and the microbial population of mouse bowel[J]. Journal of Zhejiang University Science B, 2009, 10(4): 258-263.

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author="Xiao-dong PAN, Fen-qin CHEN, Tian-xing WU, Hong-gang TANG, Zhan-yu ZHAO",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Prebiotic oligosaccharides change the concentrations of short-chain fatty acids and the microbial population of mouse bowel
%A Xiao-dong PAN
%A Fen-qin CHEN
%A Tian-xing WU
%A Hong-gang TANG
%A Zhan-yu ZHAO
%J Journal of Zhejiang University SCIENCE B
%V 10
%N 4
%P 258-263
%@ 1673-1581
%D 2009
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B0820261

T1 - Prebiotic oligosaccharides change the concentrations of short-chain fatty acids and the microbial population of mouse bowel
A1 - Xiao-dong PAN
A1 - Fen-qin CHEN
A1 - Tian-xing WU
A1 - Hong-gang TANG
A1 - Zhan-yu ZHAO
J0 - Journal of Zhejiang University Science B
VL - 10
IS - 4
SP - 258
EP - 263
%@ 1673-1581
Y1 - 2009
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B0820261

The purpose of this study was to clarify effects of selected oligosaccharides on concentrations of cecal short-chain fatty acids (SCFAs), total large bowel wet weight and wall weight, and cecal microbiota levels in mice. Mice were respectively given gavage of selected fructooligosaccharides (FOS), galactooligosaccharides (GOS), mannanoligosaccharides (MOS), and chitooligosaccharides (COS) [1000 mg/(kg body weight·d)]. Control group was given physiological saline solution. After 14 d treatment, SCFAs and lactate in mice cecum were significantly increased (P<0.05) by intake of oligosaccharides, especially FOS and GOS. Thus, providing these oligosaccharides as ingredients in nutritional formulas may benefit the gastrointestinal tract.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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