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Journal of Zhejiang University SCIENCE B 2011 Vol.12 No.12 P.983-989


Gastric motility functional study based on electrical bioimpedance measurements and simultaneous electrogastrography

Author(s):  Zhang-yong Li, Chao-shi Ren, Shu Zhao, Hong Sha, Juan Deng

Affiliation(s):  College of Bioinformation, Chongqing University of Posts and Telecommunications, Chongqing 400065, China, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China

Corresponding email(s):   renbme@163.com

Key Words:  Gastric motility, Electrical bioimpedance, Electrogastrography, Functional dyspepsia, Gastritis

Zhang-yong Li, Chao-shi Ren, Shu Zhao, Hong Sha, Juan Deng. Gastric motility functional study based on electrical bioimpedance measurements and simultaneous electrogastrography[J]. Journal of Zhejiang University Science B, 2011, 12(12): 983-989.

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publisher="Zhejiang University Press & Springer",

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%T Gastric motility functional study based on electrical bioimpedance measurements and simultaneous electrogastrography
%A Zhang-yong Li
%A Chao-shi Ren
%A Shu Zhao
%A Hong Sha
%A Juan Deng
%J Journal of Zhejiang University SCIENCE B
%V 12
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%P 983-989
%@ 1673-1581
%D 2011
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1000436

T1 - Gastric motility functional study based on electrical bioimpedance measurements and simultaneous electrogastrography
A1 - Zhang-yong Li
A1 - Chao-shi Ren
A1 - Shu Zhao
A1 - Hong Sha
A1 - Juan Deng
J0 - Journal of Zhejiang University Science B
VL - 12
IS - 12
SP - 983
EP - 989
%@ 1673-1581
Y1 - 2011
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1000436

For some time now, the research on gastric motility and function has fallen behind in the amount of research on gastric endocrine, exocrine secretion, and gastric morphology. In this paper, a noninvasive method to study gastric motility was developed, taking bioimpedance measurements over the gastric area simultaneously with the electrogastrography (EGG). This is based on the concept of observing and analyzing simultaneously the intrinsic electrical gastric activity (basic electric rhythm) and the mechanical gastric activity. Additionally, preliminary clinical studies of healthy subjects and subjects with functional dyspepsia (FD) and gastritis were carried out. The impedance gastric motility (IGM) measurements of the healthy and FD subjects were compared, along with the studies of the FD subjects before treatment and after one week and three weeks of treatment. We also compared IGM measurements of healthy subjects and subjects with erosive gastritis, along with the studies of the subjects with erosive gastritis before treatment and after one week of treatment. Results show that FD subjects have poor gastric motility (P<0.01). After a week of treatment, the gastric motility of FD subjects was not yet improved although the EGG had returned to normal by this time. By three weeks of treatment, the regular IGM rhythm returned in FD subjects. There was a significant difference of IGM parameters between the gastritis and healthy subjects (P<0.05). The EGG rhythm of the gastritis subjects returned to normal at one week post-treatment, while IGM parameters showed a trend to improvement (P>0.05), These results suggest the possibility of clinic application of the proposed method.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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