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Received: 2018-12-14

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Journal of Zhejiang University SCIENCE B 2019 Vol.20 No.8 P.670-678


Adult sacrococcygeal teratoma: a retrospective study over eight years at a single institution

Author(s):  Xiang-Ming Xu, Feng Zhao, Xiao-Fei Cheng, Wei-Xiang Zhong, Jing-Peng Liu, Wei-Qin Jiang, Xiao-Kai Yu, Jian-Jiang Lin

Affiliation(s):  Department of Colorectal Surgery, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China; more

Corresponding email(s):   xuxiangming@zju.edu.cn, yuxiaokai@zju.edu.cn

Key Words:  Sacrococcygeal teratoma (SCT), Clinical features, Computed tomography (CT), Magnetic resonance imaging (MRI), Surgical resection modality

Xiang-Ming Xu, Feng Zhao, Xiao-Fei Cheng, Wei-Xiang Zhong, Jing-Peng Liu, Wei-Qin Jiang, Xiao-Kai Yu, Jian-Jiang Lin. Adult sacrococcygeal teratoma: a retrospective study over eight years at a single institution[J]. Journal of Zhejiang University Science B, 2019, 20(8): 670-678.

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author="Xiang-Ming Xu, Feng Zhao, Xiao-Fei Cheng, Wei-Xiang Zhong, Jing-Peng Liu, Wei-Qin Jiang, Xiao-Kai Yu, Jian-Jiang Lin",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Adult sacrococcygeal teratoma: a retrospective study over eight years at a single institution
%A Xiang-Ming Xu
%A Feng Zhao
%A Xiao-Fei Cheng
%A Wei-Xiang Zhong
%A Jing-Peng Liu
%A Wei-Qin Jiang
%A Xiao-Kai Yu
%A Jian-Jiang Lin
%J Journal of Zhejiang University SCIENCE B
%V 20
%N 8
%P 670-678
%@ 1673-1581
%D 2019
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1800621

T1 - Adult sacrococcygeal teratoma: a retrospective study over eight years at a single institution
A1 - Xiang-Ming Xu
A1 - Feng Zhao
A1 - Xiao-Fei Cheng
A1 - Wei-Xiang Zhong
A1 - Jing-Peng Liu
A1 - Wei-Qin Jiang
A1 - Xiao-Kai Yu
A1 - Jian-Jiang Lin
J0 - Journal of Zhejiang University Science B
VL - 20
IS - 8
SP - 670
EP - 678
%@ 1673-1581
Y1 - 2019
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1800621

Objective: To determine the clinical, imaging, and histological features, and surgical resection modalities and outcomes of adult sacrococcygeal teratoma (SCT). Methods: Adult patients with histopathologically diagnosed SCT were enrolled in our hospital between August 2010 and August 2018. Each patient’s characteristics and clinical information were reviewed. Results: There were 8 patients in the study (2 males, 6 females) with a median age of 34 years (range, 18–67 years). The time to clinical symptoms was 14 d to 35 years, with a median time of 4 years. Six patients presented with symptoms of sacrococcygeal pain, and four with signs of sacrococcygeal mass and ulceration in the sacrococcygeal region. Six patients were evaluated using a combination of computed tomography (CT) and magnetic resonance imaging (MRI). All patients showed a presacral tumor with heterogeneous intensity on CT images. All patients underwent surgical treatment, including 6 parasacral, 1 transabdominal, and 1 combined anterior-posterior surgery cases. Seven patients were histopathologically diagnosed with benign mature SCT, and have shown no recurrence. One patient had malignant SCT, with recurrence at 84 months after surgery. After a second surgery, the patient had no recurrence within 6 months follow-up after re-resection. Conclusions: Our retrospective study demonstrated: (1) adult SCT is difficult to diagnose because of a lack of typical clinical symptoms and signs; (2) a combination of CT and MRI examination is beneficial for preoperative diagnosis; (3) the choice of surgical approach and surgical resection modality depends on the size, location, and components of the tumor, which can be defined from preoperative CT and MRI evaluation; (4) most adult SCTs are benign; the surgical outcome for the malignant SCT patient was good after complete resection. Even for the patient with recurrent malignant SCT, the surgical outcome was good after re-resection.




Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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