CLC number:
On-line Access: 2024-08-27
Received: 2023-10-17
Revision Accepted: 2024-05-08
Crosschecked: 0000-00-00
Cited: 0
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Citations: Bibtex RefMan EndNote GB/T7714
Jianwei CHANG, Chong XIE, Pei WANG, Zhenxin GU, Yongbin HAN, Runqiang YANG. Red light enhances folate accumulation in wheat seedlings[J]. Journal of Zhejiang University Science B, 2021, 22(11): 906-916.
@article{title="Red light enhances folate accumulation in wheat seedlings",
author="Jianwei CHANG, Chong XIE, Pei WANG, Zhenxin GU, Yongbin HAN, Runqiang YANG",
journal="Journal of Zhejiang University Science B",
volume="22",
number="11",
pages="906-916",
year="2021",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B2100266"
}
%0 Journal Article
%T Red light enhances folate accumulation in wheat seedlings
%A Jianwei CHANG
%A Chong XIE
%A Pei WANG
%A Zhenxin GU
%A Yongbin HAN
%A Runqiang YANG
%J Journal of Zhejiang University SCIENCE B
%V 22
%N 11
%P 906-916
%@ 1673-1581
%D 2021
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2100266
TY - JOUR
T1 - Red light enhances folate accumulation in wheat seedlings
A1 - Jianwei CHANG
A1 - Chong XIE
A1 - Pei WANG
A1 - Zhenxin GU
A1 - Yongbin HAN
A1 - Runqiang YANG
J0 - Journal of Zhejiang University Science B
VL - 22
IS - 11
SP - 906
EP - 916
%@ 1673-1581
Y1 - 2021
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B2100266
Abstract: Red, white, blue, green, and yellow lights were applied to investigate their effects on folate accumulation in wheat seedlings. The different lights, especially red light, significantly increased the total folate content. Total folate showed maximum accumulation under 30 μmol/(m2·s) of red light, with an increase of 24% compared with the control (darkness). 5-Methyl-tetrahydrofolate (5-CH3-THF) was the dominant folate component, and was significantly increased by red light irradiation. In addition, under red light, the folate content of leaves was higher and more sensitive to light than that of endosperm or roots. red light up-regulated the expression of guanosine triphosphate (GTP) cyclohydrolase 1 (GCH1) and aminodeoxychorismate synthase (ADCS), enhanced the activity of GCH1 and ADCS, and increased the content of precursors of folate synthesis, including pterin and p-aminobenzoic acid (pABA). Hence, the increased folate accumulation promoted by light could be attributed to the increased content of folate synthesis precursors, the activity of key enzymes, and related gene expression.
[1]ArifS, KhanMR, GardeziSDA, et al., 2016. A novel hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase (HPPK-DHPS) gene from a nutraceutical plant seabuckthorn, involved in folate pathway is predominantly expressed in fruit tissue. Int J Agric Biol, 18(2):412-418.
[2]AttaCAM, FiestKM, FrolkisAD, et al., 2016. Global birth prevalence of spina bifida by folic acid fortification status: a systematic review and meta-analysis. Am J Publ Health, 106(1):e24-e34.
[3]BassetGJC, QuinlivanEP, RavanelS, et al., 2004. Folate synthesis in plants: the p-aminobenzoate branch is initiated by a bifunctional PabA-PabB protein that is targeted to plastids. Proc Natl Acad Sci USA, 101(6):1496-1501.
[4]BozH, 2021. Effect of processing on cereal folates. J Cereal Sci, 99:103202.
[5]ChenZJ, MaY, WengY, et al., 2019. Effects of UV-B radiation on phenolic accumulation, antioxidant activity and physiological changes in wheat (Triticum aestivum L.) seedlings. Food Biosci, 30:100409.
[6]de la GarzaRD, GregoryJF III, HansonAD, 2007. Folate biofortification of tomato fruit. Proc Natl Acad Sci USA, 104(10):4218-4222.
[7]de LepeleireJ, StrobbeS, VerstraeteJ, et al., 2018. Folate biofortification of potato by tuber-specific expression of four folate biosynthesis genes. Mol Plant, 11(1):175-188.
[8]DhillonB, ChoudharyG, SodhiNS, 2020. A study on physicochemical, antioxidant and microbial properties of germinated wheat flour and its utilization in breads. J Food Sci Technol, 57(8):2800-2808.
[9]Długosz-GrochowskaO, KołtonA, WojciechowskaR, 2016. Modifying folate and polyphenol concentrations in Lamb’s lettuce by the use of LED supplemental lighting during cultivation in greenhouses. J Funct Foods, 26:228-237.
[10]FuHJ, ZengJ, LiuC, et al., 2021. Folate intake and risk of pancreatic cancer: a systematic review and updated meta-analysis of epidemiological studies. Dig Dis Sci, 66(7):2368-2379.
[11]GoljaMV, ŠmidA, KuželičkiNK, et al., 2020. Folate insu‑fficiency due to MTHFR deficiency is bypassed by 5-methyltetrahydrofolate. J Clin Med, 9(9):2836.
[12]GorelovaV, AmbachL, RébeilléF, et al., 2017. Folates in plants: research advances and progress in crop biofortification. Front Chem, 5:21.
[13]GorelovaV, BastienO, de ClerckO, et al., 2019. Evolution of folate biosynthesis and metabolism across algae and land plant lineages. Sci Rep, 9:5731.
[14]JabrinS, RavanelS, GambonnetB, et al., 2003. One-carbon metabolism in plants. Regulation of tetrahydrofolate synthesis during germination and seedling development. Plant Physiol, 131(3):1431-1439.
[15]KomaD, YamanakaH, MoriyoshiK, et al., 2014. Production of p-aminobenzoic acid by metabolically engineered Escherichia coli. Biosci Biotechnol Biochem, 78(2):350-357.
[16]LeeSW, SeoJM, LeeMK, et al., 2014. Influence of different LED lamps on the production of phenolic compounds in common and Tartary buckwheat sprouts. Ind Crops Prod, 54:320-326.
[17]LeeWD, PironaAC, SarvinB, et al., 2021. Tumor reliance on cytosolic versus mitochondrial one-carbon flux depends on folate availability. Cell Metab, 33(1):190-198.e6.
[18]LiangQJ, WangK, LiuXN, et al., 2019. Improved folate accumulation in genetically modified maize and wheat. J Exp Bot, 70(5):1539-1551.
[19]LiuFY, XiangN, HuJG, et al., 2017. The manipulation of gene expression and the biosynthesis of vitamin C, E and folate in light-and dark-germination of sweet corn seeds. Sci Rep, 7:7484.
[20]LiuT, HouGG, CardinM, et al., 2017. Quality attributes of whole-wheat flour tortillas with sprouted whole-wheat flour substitution. LWT, 77:1-7.
[21]MaM, WangP, YangRQ, et al., 2018. Effects of UV-B radiation on the isoflavone accumulation and physiological-biochemical changes of soybean during germination: physiological-biochemical change of germinated soybean induced by UV-B. Food Chem, 250:259-267.
[22]MartiA, CardoneG, NicolodiA, et al., 2017. Sprouted wheat as an alternative to conventional flour improvers in bread-making. LWT, 80:230-236.
[23]McIntoshSR, HenryRJ, 2008. Genes of folate biosynthesis in wheat. J Cereal Sci, 48(3):632-638.
[24]McIntoshSR, BrushettD, HenryRJ, 2008. GTP cyclohydrolase 1 expression and folate accumulation in the developing wheat seed. J Cereal Sci, 48(2):503-512.
[25]MwandoE, AngessaTT, HanY, et al., 2020. Salinity tolerance in barley during germination—homologs and potential genes. J Zhejiang Univ-Sci B (Biomed & Biotechnol), 21(2):93-121.
[26]OhJ, ParkE, SongK, et al., 2020. PHYTOCHROME INTERACTING FACTOR8 inhibits phytochrome A-mediated far-red light responses in Arabidopsis. Plant Cell, 32(1):186-205.
[27]RiazB, LiangQJ, WanX, et al., 2019. Folate content analysis of wheat cultivars developed in the North China Plain. Food Chem, 289:377-383.
[28]RiveraNGR, García-SalinasC, AragãoFJL, et al., 2016. Metabolic engineering of folate and its precursors in Mexican common bean (Phaseolus vulgaris L.). Plant Biotechnol J, 14(10):2021-2032.
[29]SamuolienėG, SirtautasR, BrazaitytėA, et al., 2012. Supplementary red-LED lighting and the changes in phytochemical content of two baby leaf lettuce varieties during three seasons. J Food Agric Environ, 10(3-4):701-706.
[30]SpalholzH, Perkins-VeazieP, HernándezR, 2020. Impact of sun-simulated white light and varied blue: red spectrums on the growth, morphology, development, and phytochemical content of green-and red-leaf lettuce at different growth stages. Sci Hortic, 264:109195.
[31]StrobbeS, van der StraetenD, 2017. Folate biofortification in food crops. Curr Opin Biotechnol, 44:202-211.
[32]TaulavuoriK, PyysaloA, TaulavuoriE, et al., 2018. Responses of phenolic acid and flavonoid synthesis to blue and blue-violet light depends on plant species. Environ Exp Bot, 150:183-187.
[33]WatanabeS, OhtaniY, TatsukamiY, et al., 2017. Folate biofortification in hydroponically cultivated spinach by the addition of phenylalanine. J Agric Food Chem, 65(23):4605-4610.
[34]YangF, FengLY, LiuQL, et al., 2018. Effect of interactions between light intensity and red-to-far-red ratio on the photosynthesis of soybean leaves under shade condition. Environ Exp Bot, 150:79-87.
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