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Journal of Zhejiang University SCIENCE B 1998 Vol.-1 No.-1 P.

http://doi.org/10.1631/jzus.B2300864


Pharmacotherapy for the core symptoms of autism spectrum disorder


Author(s):  Peiying TAN, Xiaolin SHEN, Lizhang ZENG, Xuchu WENG, Hongyan GENG1, 2

Affiliation(s):  Key Laboratory of Brain, Cognition and Education Sciences, Ministry of Education, South China Normal University, Guangzhou 510631, China; more

Corresponding email(s):   snail.yanzi@163.com

Key Words:  Autism spectrum disorders, core symptoms, pharmacotherapy, repetitive behaviors, social dysfunction


Peiying TAN, Xiaolin SHEN, Lizhang ZENG, Xuchu WENG, Hongyan GENG1,2. Pharmacotherapy for the core symptoms of autism spectrum disorder[J]. Journal of Zhejiang University Science B, 1998, -1(-1): .

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Abstract: 
Autism Spectrum Disorder (ASD) is a range of neurodevelopmental diseases characterized by social dysfunction and stereotypic behaviors. The etiology of ASD remains largely unexplored, resulting in a diverse array of described clinical manifestations and varying degrees of severity. Currently, there are no drugs approved by a supervisory organization that can effectively treat the core symptoms of ASD. Childhood and adolescence are crucial stages for making significant achievements in ASD treatment, necessitating the development of drugs specifically for these periods. Based on the drug targets and mechanisms of action, it can be found that atypical psychotropic medications, anti-inflammatory and antioxidant medications, hormonal medications, ion channel medications, and gastrointestinal medications have shown significant improvement in treating the core symptoms of ASD in both children and adolescents. In addition, comparisons of drugs within the same category regarding efficacy and safety have been made to identify better alternatives and promote drug development. While further evaluation of the effectiveness and safety of these medications is needed, they hold great potential for widespread application in the clinical treatment of the principal symptoms of ASD.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

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