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Bio-Design and Manufacturing  2018 Vol.1 No.2 P.89-100

http://doi.org/10.1007/s42242-018-0013-2


3D biofabrication for tubular tissue engineering


Author(s):  Ian Holland, Jack Logan, Jiezhong Shi, Christopher McCormick, Dongsheng Liu, Wenmiao Shu

Affiliation(s):  Department of Biomedical Engineering, University of Strathclyde, Glasgow G1 1QE, UK; more

Corresponding email(s):   liudongsheng@mail.tsinghua.edu.cn, will.shu@strath.ac.uk

Key Words:  Tubular organs Tissue engineering 3D printing Bio-inks


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Ian Holland,Jack Logan,Jiezhong Shi,Christopher McCormick,Dongsheng Liu,Wenmiao Shu . 3D biofabrication for tubular tissue engineering[J]. Journal of Zhejiang University Science D, 2018, 1(2): 89-100.

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Abstract: 
The therapeutic replacement of diseased tubular tissue is hindered by the availability and suitability of current donor, autologous and synthetically derived protheses. Artificially created, tissue engineered, constructs have the potential to alleviate these concerns with reduced autoimmune response, high anatomical accuracy, long-term patency and growth potential. The advent of 3D bioprinting technology has further supplemented the technological toolbox, opening up new biofabrication research opportunities and expanding the therapeutic potential of the field. In this review, we highlight the challenges facing those seeking to create artificial tubular tissue with its associated complex macro- and microscopic architecture. Current biofabrication approaches, including 3D printing techniques, are reviewed and future directions suggested.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

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