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Tackling iron deficiency: the multifunctional benefits of biopolysaccharide-iron(III) complexes from traditional Chinese medicinal plants
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Wenyang ZHAO1,2, Chun-Wai MAI3, Kai Bin LIEW4, Siew-Keah LEE5, Wei DU6, Li CHEN7, Gabriel Akyirem AKOWUAH8, Yik-Ling CHEW1. Tackling iron deficiency: the multifunctional benefits of biopolysaccharide-iron(III) complexes from traditional Chinese medicinal plants[J]. Journal of Zhejiang University Science B, 1998, -1(-1): .
@article{title="Tackling iron deficiency: the multifunctional benefits of biopolysaccharide-iron(III) complexes from traditional Chinese medicinal plants",
author="Wenyang ZHAO1,2, Chun-Wai MAI3, Kai Bin LIEW4, Siew-Keah LEE5, Wei DU6, Li CHEN7, Gabriel Akyirem AKOWUAH8, Yik-Ling CHEW1",
journal="Journal of Zhejiang University Science B",
volume="-1",
number="-1",
pages="",
year="1998",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B2500114"
}
%0 Journal Article
%T Tackling iron deficiency: the multifunctional benefits of biopolysaccharide-iron(III) complexes from traditional Chinese medicinal plants
%A Wenyang ZHAO1
%A 2
%A Chun-Wai MAI3
%A Kai Bin LIEW4
%A Siew-Keah LEE5
%A Wei DU6
%A Li CHEN7
%A Gabriel Akyirem AKOWUAH8
%A Yik-Ling CHEW1
%J Journal of Zhejiang University SCIENCE B
%V -1
%N -1
%P
%@ 1673-1581
%D 1998
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2500114
TY - JOUR
T1 - Tackling iron deficiency: the multifunctional benefits of biopolysaccharide-iron(III) complexes from traditional Chinese medicinal plants
A1 - Wenyang ZHAO1
A1 - 2
A1 - Chun-Wai MAI3
A1 - Kai Bin LIEW4
A1 - Siew-Keah LEE5
A1 - Wei DU6
A1 - Li CHEN7
A1 - Gabriel Akyirem AKOWUAH8
A1 - Yik-Ling CHEW1
J0 - Journal of Zhejiang University Science B
VL - -1
IS - -1
SP -
EP -
%@ 1673-1581
Y1 - 1998
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B2500114
Abstract: Traditional Chinese Medicinal (TCM) plants are known to contain bioactive ingredients, including beneficial biopolysaccharides that may also serve as excipients in drug formulation and delivery. Some of these biopolysaccharides also exhibit a wide range of biological activities. Biopolysaccharides have also been used in the development of biopolysaccharide-iron complexes that are characterized by high iron content, low gastrointestinal irritation and enhanced bioavailability, helping to overcome the limitations of conventional iron supplements. This review focuses on the unique properties of TCM-derived biopolysaccharides in addressing these limitations and highlights their bioavailability and therapeutic potential, including their roles in iron release and delivery, gastroprotective effects, blood sugar regulation, and antioxidant activity, as demonstrated in in vitro and in vivo experiments and clinical trials. The adverse reactions, safety profile and structureactivity relationship of biopolysaccharide-iron complexes in antioxidant activities are also thoroughly discussed. Supplementation with these next-generation iron complexes may represent a promising strategy for the treatment of iron deficiency anaemia and the promotion of overall human health and well-being.
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