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Ziang WANG, Teng WANG, Yidi ZHANG, Wenhui CHENG, Xin'e SHI, Yuqi LV, Jianjun JIN. Recent research advances in the biological function and molecular mechanism of methylmalonic acid[J]. Journal of Zhejiang University Science B, 1998, -1(-1): .
@article{title="Recent research advances in the biological function and molecular mechanism of methylmalonic acid",
author="Ziang WANG, Teng WANG, Yidi ZHANG, Wenhui CHENG, Xin'e SHI, Yuqi LV, Jianjun JIN",
journal="Journal of Zhejiang University Science B",
volume="-1",
number="-1",
pages="",
year="1998",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B2400202"
}
%0 Journal Article
%T Recent research advances in the biological function and molecular mechanism of methylmalonic acid
%A Ziang WANG
%A Teng WANG
%A Yidi ZHANG
%A Wenhui CHENG
%A Xin'e SHI
%A Yuqi LV
%A Jianjun JIN
%J Journal of Zhejiang University SCIENCE B
%V -1
%N -1
%P
%@ 1673-1581
%D 1998
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2400202
TY - JOUR
T1 - Recent research advances in the biological function and molecular mechanism of methylmalonic acid
A1 - Ziang WANG
A1 - Teng WANG
A1 - Yidi ZHANG
A1 - Wenhui CHENG
A1 - Xin'e SHI
A1 - Yuqi LV
A1 - Jianjun JIN
J0 - Journal of Zhejiang University Science B
VL - -1
IS - -1
SP -
EP -
%@ 1673-1581
Y1 - 1998
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B2400202
Abstract: The abnormal accumulation of methylmalonic acid (MMA), the leading cause of methylmalonic acidemia, can cause irreversible damage to the brain, kidney and cardiovascular system. In addition, the accumulation of MMA in the blood has recently been associated with the occurrence of cancer, restricted bodily movement and growth retardation. In this review, recent studies on the relationship between the metabolic abnormality of MMA and disease occurrence were summarized concerning the brain, kidney, cardiovascular system, cancer, and skeletal muscles, providing a theoretical basis and reference for further research and the treatment of MMA-related pathophysiological changes.
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