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Received: 2019-04-24

Revision Accepted: 2019-08-12

Crosschecked: 2020-03-03

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Chen-lei Pang


Qing Yang


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Frontiers of Information Technology & Electronic Engineering  2020 Vol.21 No.8 P.1134-1149


Chip-based waveguides for high-sensitivity biosensing and super-resolution imaging

Author(s):  Chen-lei Pang, Xu Liu, Wei Chen, Qing Yang

Affiliation(s):  State Key Laboratory of Modern Optical Instrumentation, College of Optical Science and Engineering, Zhejiang University, Hangzhou 310027, China; more

Corresponding email(s):   qingyang@zju.edu.cn

Key Words:  Waveguide-based sensing, Waveguide-based imaging, Evanescent illumination, Frequency shifting and stitching

Chen-lei Pang, Xu Liu, Wei Chen, Qing Yang. Chip-based waveguides for high-sensitivity biosensing and super-resolution imaging[J]. Frontiers of Information Technology & Electronic Engineering, 2020, 21(8): 1134-1149.

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T1 - Chip-based waveguides for high-sensitivity biosensing and super-resolution imaging
A1 - Chen-lei Pang
A1 - Xu Liu
A1 - Wei Chen
A1 - Qing Yang
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PB - Zhejiang University Press & Springer
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DOI - 10.1631/FITEE.1900211

In this review, we introduce some chip-based waveguide biosensing and imaging techniques, which significantly reduce the complexity of the entire system. These techniques use a well-confined evanescent field to interact with the surrounding materials and achieve high sensitivity sensing and high signal-to-noise ratio (SNR) super-resolution imaging. The fabrication process of these chips is simple and compatible with conventional semiconductor fabrication methods, allowing high-yield production. Combined with recently developed chip-based light sources, these techniques offer the possibility of biosensing and super-resolution imaging based on integrated circuits.





Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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