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Journal of Zhejiang University SCIENCE A 2001 Vol.2 No.4 P.453-455

http://doi.org/10.1631/jzus.2001.0453


MOTILIN LEVELS AND ELECTROGASTROENTEROGRAM STUDIES IN HYPOTHYROIDISM


Author(s):  WANG Hang-yong, CAO Qian, LI You-ming

Affiliation(s):  First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China; more

Corresponding email(s): 

Key Words:  hypothyroidism, motilin, electrogastroenterogram


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WANG Hang-yong, CAO Qian, LI You-ming. MOTILIN LEVELS AND ELECTROGASTROENTEROGRAM STUDIES IN HYPOTHYROIDISM[J]. Journal of Zhejiang University Science A, 2001, 2(4): 453-455.

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DOI - 10.1631/jzus.2001.0453


Abstract: 
To study the relationship between gastrointestinal dysfunction and motilin in patients with hypot- hyroidism. The plasma motilin concentration was measured by radiommunoassay(RIA) in 30 patients with hypothyroidism and also in 30 controls. At the same time, the electrogastroenterogram was also taken. Among the hypothyroidism patients, 56.6% had decreased gastric motility, especially in gastric body and greater gastric curvature; 86.6 % had decreased colonic motility, especially in the left half of the colon. There were no significant differences of plasma motilin concentration between patients with hypothyroidism and controls (P>0.05). There were also no differences between pre-treatment and pest-treatment individuals, but significant differences were observed in the electrogastroenterogram. We conclude that the plasma motilin eoncertration in hypothyroidism patients was the same as that in normal patients, and that electrogastmenterogram studies in patients with gastrointestinal dysfunction may be valuable.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference

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[3] Vaezi, M.F., Richter, J.E., 1997. Contribution of acid and duodenogastro-eesophageal reflux to oesophageal mucosal injury and symptoms in partial gastroectomy patients. Gut, 41:297-302.

[4] Wang, H.Y., Ji, F., Fang, L.L. et al., 1992. Prehminary study on relationship between EGG pattern and clinical symptoms. Journal of zhejiang medical university. 21(4):172-173.

[5] Wang, H.Y., Lin, X.J., Chen, Z.Y. et al., 1993. Preliminary study on relationship between gastric allorhythmia and gastric dysperiatalsis. Journal of Gastroenterology and Hepatology, 8(suppl 2):s236.

[6] Wang, H.Y., Fang, L.L., Wang, Q.Y. et al., 1995. The analysis 34 cases of determination by electroenterograph. Chinese journal of new gastroenterology. 3(suppl 3):145-146.

[7] Xu, G.M., Zou, D.W.,Yin, N., et al., 1998. 24-Hour electrogastrogram in healthy volunteers. Chin J Digestion, 18(2):76-78.

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