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Received: 2007-01-31

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Journal of Zhejiang University SCIENCE B 2007 Vol.8 No.9 P.616-619


Amniotic membrane transplantation for porous sphere orbital implant exposure

Author(s):  CHEN Yan-hong, CUI Hong-guang

Affiliation(s):  Department of Eye Center, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310015, China

Corresponding email(s):   chenyhmd@yahoo.com.cn, chg96@hzcnc.com

Key Words:  Amniotic membrane transplantation, Orbital implants, Exposure

CHEN Yan-hong, CUI Hong-guang. Amniotic membrane transplantation for porous sphere orbital implant exposure[J]. Journal of Zhejiang University Science B, 2007, 8(9): 616-619.

@article{title="Amniotic membrane transplantation for porous sphere orbital implant exposure",
author="CHEN Yan-hong, CUI Hong-guang",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Amniotic membrane transplantation for porous sphere orbital implant exposure
%A CHEN Yan-hong
%A CUI Hong-guang
%J Journal of Zhejiang University SCIENCE B
%V 8
%N 9
%P 616-619
%@ 1673-1581
%D 2007
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2007.B0616

T1 - Amniotic membrane transplantation for porous sphere orbital implant exposure
A1 - CHEN Yan-hong
A1 - CUI Hong-guang
J0 - Journal of Zhejiang University Science B
VL - 8
IS - 9
SP - 616
EP - 619
%@ 1673-1581
Y1 - 2007
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2007.B0616

Objective: This study is aimed at describing the clinical outcome of amniotic membrane transplantation for exposure of porous sphere implants. Methods: A retrospective review of consecutive cases of porous sphere orbital implant exposure was carried out. Eight cases were presented between May 2004 and Oct. 2006 (5 males, 3 females; mean age 44.5 years). Six had enucleation and two had evisceration. exposure occurred in two primary and six secondary. Orbital implant diameter was 22 mm in seven cases and 20 mm in one case. Six patients are with hydroxyapatite and two with high-density porous polyethylene (Medpor) orbital implants. The mean time from implantation to exposure was 1.1 months (range 0.8~2 months). All patients required surgical intervention. Results: The time of follow-up ranged from 3.0 to 28.0 months (mean 16.5 months). Amniotic membrane grafting successfully closed the defect without re-exposure in all of these patients. The grafts were left bare with a mean time to conjunctiva of about 1 month (range 0.8~1.5 months). Conclusion: Exposed porous sphere implants were treated successfully with amniotic membrane graft in all of patients. The graft is easy to harvest. This technique is useful, dose not lead to prolonged socket inflammation and infection, and it is valuable application extensively.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


[1] Buetiner, H., Bartley, G.B., 1992. Tissue breakdown and exposure associated with orbital hydroxyapatite implants. Am. J. Ophthalmol., 113(6):669-673.

[2] Christmas, N.J., Gordon, C.D., Murray, T.G., Tse, D., Johnson, T., Garonzil, S., O′Brien, J.M., 1998. Intraorbital implants after enucleation and their complications: a 10-year review. Arch. Ophthalmol., 116(9):1199-1203.

[3] Danz, W., 1990. Mobility implants: a review. Adv. Ophthalmic Plast. Reconstr. Surg., 8:46-52.

[4] Fan, J.T., Robertson, D.M., 1995. Long-term follow-up of the Allen implant, 1967 to 1991. Ophthalmology, 102(3):510-516.

[5] Inkster, C.F., Ng, S.G., Leatherbarrow, B., 1994. Primary banked scleral patch graft in the prevention of exposure of hydroxyapatite orbital implants. Ophthalmology, 109(2):398-392.

[6] Karesh, J.W., Dresner, S.C., 1994. High-density porous polyethylene (Medpor) as a successful anophthalmic socket implant. Ophthalmology, 101(10):1688-1695 (Discussion in p.1695-1696).

[7] Lee, V., Subark, S.I., Hungerford, J.L., Davies, N.P., Logani, S., 2000. Exposure of primary orbital implants in postenucleation retinoblastoma patients. Ophthalmology, 107(5):940-946.

[8] Martin, P., Ghabrial, R., 1998. Repair of exposed hydroxyapatite orbital implant by a tarsoconjunctival pedicle flap. Ophthalmology, 105(9):1694-1697.

[9] McNab, A., 1995. Hydroxyapatite orbital implants. Experience with 100 cases. Aust. N. Z. J. Ophthalmol., 23(2):117-123.

[10] Nakamura, T., Yoshitani, M., Rigby, H., Fullwood, N.J., Ito, W., Inatomi, T., Sotozono, C., Nakamura, T., Shimizu, Y., Kinoshita, S., 2004. Human sterilized freeze-dried amniotic membrane: a useful substrate for ocular surface reconstruction. Invest. Ophthalmol. Vis. Sci., 45(1):93-99.

[11] Oestreicher, J.H., Liu, E., Berkowitez, M., 1997. Complications of hydroxyapatite orbital implants. A review of 100 consecutive cases and a comparison of Dexon mesh (polyglycolic acid) with scleral wrapping. Ophthalmology, 104(2):324-329.

[12] Remulla, H.D., Rubin, P.A., Shore, J.W., Sutula, F.C., Townsend, D.J., Woog, J.J., Jahrling, K.V., 1995. Complications of porous spherical orbital implants. Ophthalmology, 102(4):586-593.

[13] Sagoo, M.S., Olver, J.M., 2004. Autogenous temporalis fascia patch graft for porous polyethylene (Medpor) sphere orbital implant exposure. Br. J. Ophthalmol., 88(7):942-946.

[14] Shields, C.L., Shields, J.A., de Potter, P., Singh, A.D., 1993. Lack of complications of the hydroxyapatite orbital implant in 250 consecutive cases. Trans. Am. Ophthalmol. Soc., 91:177-189.

[15] Solomon, A., Espana, E.M., Tseng, S.C., 2003. Amniotic membrane transplantation for reconstruction of the conjunctival fornices. Ophthalmology, 110(1):93-100.

[16] van Acker, E., de Potter, P., 2001. Implant orbitaire en polyethylene poreux (Medpor). J. Fr. Ophthalmol., 24(10):1067-1073 (in French).

[17] Yoon, D.K., Robert, A.G., Norman, S., 1994. Management of exposed hydroxyapatite orbital implants. Ophthalmology, 101(10):1709-1715.

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