Full Text:   <2002>

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CLC number: TG146.13; TG665; R318.08

On-line Access: 2020-11-11

Received: 2020-04-27

Revision Accepted: 2020-06-03

Crosschecked: 2020-10-16

Cited: 0

Clicked: 3570

Citations:  Bibtex RefMan EndNote GB/T7714


You-wen Yang


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Journal of Zhejiang University SCIENCE A 2020 Vol.21 No.11 P.876-891


Forming quality, mechanical properties, and anti-inflammatory activity of additive manufactured Zn–Nd alloy

Author(s):  Ci-jun Shuai, Ming-li Yang, Fang Deng, You-wen Yang, Shu-ping Peng, Fang-wei Qi, Chong-xian He, Li-da Shen, Hui-xin Liang

Affiliation(s):  Institute of Bioadditive Manufacturing, Jiangxi University of Science and Technology, Nanchang 330013, China; more

Corresponding email(s):   yangyouwen@csu.edu.cn, shuping@csu.edu.cn

Key Words:  Zn–, Nd alloy, Laser powder bed fusion (LPBF), Anti-inflammatory activity, Mechanical properties

Ci-jun Shuai, Ming-li Yang, Fang Deng, You-wen Yang, Shu-ping Peng, Fang-wei Qi, Chong-xian He, Li-da Shen, Hui-xin Liang. Forming quality, mechanical properties, and anti-inflammatory activity of additive manufactured Zn–Nd alloy[J]. Journal of Zhejiang University Science A, 2020, 21(11): 876-891.

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author="Ci-jun Shuai, Ming-li Yang, Fang Deng, You-wen Yang, Shu-ping Peng, Fang-wei Qi, Chong-xian He, Li-da Shen, Hui-xin Liang",
journal="Journal of Zhejiang University Science A",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Forming quality, mechanical properties, and anti-inflammatory activity of additive manufactured Zn–Nd alloy
%A Ci-jun Shuai
%A Ming-li Yang
%A Fang Deng
%A You-wen Yang
%A Shu-ping Peng
%A Fang-wei Qi
%A Chong-xian He
%A Li-da Shen
%A Hui-xin Liang
%J Journal of Zhejiang University SCIENCE A
%V 21
%N 11
%P 876-891
%@ 1673-565X
%D 2020
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.A2000186

T1 - Forming quality, mechanical properties, and anti-inflammatory activity of additive manufactured Zn–Nd alloy
A1 - Ci-jun Shuai
A1 - Ming-li Yang
A1 - Fang Deng
A1 - You-wen Yang
A1 - Shu-ping Peng
A1 - Fang-wei Qi
A1 - Chong-xian He
A1 - Li-da Shen
A1 - Hui-xin Liang
J0 - Journal of Zhejiang University Science A
VL - 21
IS - 11
SP - 876
EP - 891
%@ 1673-565X
Y1 - 2020
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.A2000186

Zinc (Zn) has recently been recognized as a promising bone repair material due to its inherent biodegradability and favorable biocompatibility. In this work, rare earth neodymium (Nd) was introduced into a Zn-based alloy fabricated using a laser powder bed fusion (LPBF) process. Results showed that addition of Nd significantly improved the melt fluidity and reduced the evaporation of Zn, thereby achieving parts with a high densification rate of 98.71%. Significantly, the nd alloying treatment effectively refined the grain size from 25.3 to 6.2 μm. NdZn5 eutectics precipitated and contributed to a second-phase strengthening effect. As a result, the tensile strength increased to (119.3±5.1) MPa and the Vickers hardness to (76.2±4.1). Moreover, the zn–;nd alloy exhibited good anti-inflammatory activity, as the Nd ions released during degradation had a strong affinity with cell membrane phospholipids and consequently inhibited the release of inflammatory cytokines. It also presented favorable cytocompatibility, showing great potential as a bone repair material.


创新点:1. 在增材制造过程中,添加钕能够有效改善锌基合金的成形质量;2. 稀土钕提高了锌基合金的力学性能,同时也赋予了抗炎活性.
方法:1. 通过实验对比锌钕合金的表面形貌,计算出相应的致密度,并分析钕对锌基合金成形质量的影响(图2);2. 基于不同实验对比锌钕合金的微观组织结构及力学强度的变化,并探讨稀土钕提高力学性能的原因(图3~5和表1);3. 通过电化学实验和浸泡实验,分析稀土钕对降解性能的影响(图6和7);4. 基于体外生物学实验,对比分析钕对抗炎活性和细胞活性的影响(图8和9).
结论:1. 稀土钕提高了激光增材制造锌合金的成形质量,并使其致密化率高达98.71%;2. 钕合金化有助于晶粒细化和第二相强化,使极限抗拉强度提高到了(119.3±5.1) MPa;3. 钕合金化能抑制促炎因子的释放,促进抗炎因子的释放,进而使锌钕部分具有良好的抗炎活性,而细胞培养试验也表明其具有良好的生物相容性.


Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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