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CLC number: R737.1

On-line Access: 2010-04-28

Received: 2009-08-13

Revision Accepted: 2010-02-22

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Journal of Zhejiang University SCIENCE B 2010 Vol.11 No.5 P.386-389

http://doi.org/10.1631/jzus.B0900250


Metachronous contralateral testicular and bilateral adrenal metastasis of chromophobe renal cell carcinoma: a case report and review of the literature


Author(s):  Hai-yang Wu, Li-wei Xu, You-yun Zhang, Yan-lan Yu, Xin-de Li, Gong-hui Li

Affiliation(s):  Department of Urology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China

Corresponding email(s):   ligonghui1970@hotmail.com

Key Words:  Renal cell carcinoma (RCC), Testicular metastasis, Adrenal metastasis, Metastasectomy


Hai-yang Wu, Li-wei Xu, You-yun Zhang, Yan-lan Yu, Xin-de Li, Gong-hui Li. Metachronous contralateral testicular and bilateral adrenal metastasis of chromophobe renal cell carcinoma: a case report and review of the literature[J]. Journal of Zhejiang University Science B, 2010, 11(5): 386-389.

@article{title="Metachronous contralateral testicular and bilateral adrenal metastasis of chromophobe renal cell carcinoma: a case report and review of the literature",
author="Hai-yang Wu, Li-wei Xu, You-yun Zhang, Yan-lan Yu, Xin-de Li, Gong-hui Li",
journal="Journal of Zhejiang University Science B",
volume="11",
number="5",
pages="386-389",
year="2010",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B0900250"
}

%0 Journal Article
%T Metachronous contralateral testicular and bilateral adrenal metastasis of chromophobe renal cell carcinoma: a case report and review of the literature
%A Hai-yang Wu
%A Li-wei Xu
%A You-yun Zhang
%A Yan-lan Yu
%A Xin-de Li
%A Gong-hui Li
%J Journal of Zhejiang University SCIENCE B
%V 11
%N 5
%P 386-389
%@ 1673-1581
%D 2010
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B0900250

TY - JOUR
T1 - Metachronous contralateral testicular and bilateral adrenal metastasis of chromophobe renal cell carcinoma: a case report and review of the literature
A1 - Hai-yang Wu
A1 - Li-wei Xu
A1 - You-yun Zhang
A1 - Yan-lan Yu
A1 - Xin-de Li
A1 - Gong-hui Li
J0 - Journal of Zhejiang University Science B
VL - 11
IS - 5
SP - 386
EP - 389
%@ 1673-1581
Y1 - 2010
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B0900250


Abstract: 
Chromophobe renal cell carcinoma (ChRCC) metastatic to the testis has not, to the best of our knowledge, been reported in the literature. Nor have there been reports of delayed bilateral adrenal metastasis of ChRCC. Here we report a case of metachronous contralateral testicular and bilateral adrenal metastasis of ChRCC in a 70-year-old man who underwent right radical nephrectomy for RCC six years ago. He was admitted to the hospital because of left intrascrotal enlargement of two-month duration. Ultrasonography revealed a mass in the upper pole of the left testis. Computed tomography (CT) showed irregular masses in the bilateral adrenal area. Left radical orchiectomy and laparoscopic bilateral adrenalectomy were performed. The pathologic examination showed metastatic ChRCC in the left testis and bilateral adrenal gland. Postoperative follow-up showed that the patient had survived for at least 56 months without recurrence. The case highlights the unique behavior of RCC with an unusual site of metastasis and favorable survival after multiple metastasectomy.

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