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On-line Access: 2011-04-06

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Journal of Zhejiang University SCIENCE B 2011 Vol.12 No.4 P.298-302


A case study of imported pulmonary coccidioidomycosis

Author(s):  Zheng-yang Wang, Sheng-lan Wen, Ke-jing Ying

Affiliation(s):  Department of Respiratory Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China

Corresponding email(s):   yingsrrsh@163.com

Key Words:  Coccidioidomycosis, Imported disease, Pulmonary fungal infection, Endemic disease

Zheng-yang Wang, Sheng-lan Wen, Ke-jing Ying. A case study of imported pulmonary coccidioidomycosis[J]. Journal of Zhejiang University Science B, 2011, 12(4): 298-302.

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author="Zheng-yang Wang, Sheng-lan Wen, Ke-jing Ying",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

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%T A case study of imported pulmonary coccidioidomycosis
%A Zheng-yang Wang
%A Sheng-lan Wen
%A Ke-jing Ying
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%V 12
%N 4
%P 298-302
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%D 2011
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1000261

T1 - A case study of imported pulmonary coccidioidomycosis
A1 - Zheng-yang Wang
A1 - Sheng-lan Wen
A1 - Ke-jing Ying
J0 - Journal of Zhejiang University Science B
VL - 12
IS - 4
SP - 298
EP - 302
%@ 1673-1581
Y1 - 2011
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1000261

coccidioidomycosis is an endemic disease of the Western hemisphere. The cases in non-endemic areas are mostly imported. Determining a history of exposure is critical for performing the diagnosis of coccidioidomycosis, especially for cases occurring in a non-endemic area. In this study, a 71-year-old Chinese male presented to our hospital with chronic cough and malaise, and was found to have a mass in the middle lobe of right lung. He had been visiting Arizona, USA for four months before admission. Pulmonary coccidioidomycosis was confirmed by the results of histopathological examination after lobectomy. Typical microscopic features of Coccidioides are definitely diagnostic, but need be differentiated from other budding yeast infection or carcinoma histopathologically.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


[1]Batura-Gabryel, H., Brajer, B., 2008. Coccidioidomycosis in a 38-year-old man: a case report. Pol. Arch. Med. Wewn., 118(6):387-390.

[2]Bialek, R., Gonzalez, G.M., Begerow, D., Zelck, U.E., 2005. Coccidioidomycosis and blastomycosis: advances in molecular diagnosis. FEMS Immunol. Med. Microbiol., 45(3):355-360.

[3]CDC (Centers for Disease Control and Prevention), 2009. Increase in coccidioidomycosis—California, 2000–2007. MMWR Morb. Mortal. Wkly Rep., 58(5):105-109.

[4]Desai, S.A., Minai, O.A., Gordon, S.M., O′Neil, B., Wiedemann, H.P., Arroliga, A.C., 2001. Coccidioidomycosis in non-endemic areas: a case series. Respir. Med., 95(4):305-309.

[5]Futsuki, Y., Nagashima, S., Yamamoto, Y., Araki, J., Asai, S., Sawatari, K., Maesaki, S., Kohno, S., 2000. An imported case of primary pulmonary coccidioidomycosis. Kansenshogaku Zasshi, 74(7):580-584 (in Japanese).

[6]Gaidici, A., Saubolle, M.A., 2009. Transmission of coccidioidomycosis to a human via a cat bite. J. Clin. Microbiol., 47(2):505-506.

[7]Galgiani, J.N., Ampel, N.M., Blair, J.E., Catanzaro, A., Johnson, R.H., Stevens, D.A., Williams, P.L., 2005. Coccidioidomycosis. Clin. Infect. Dis., 41(9):1217-1223.

[8]Hector, R.F., Laniado-Laborin, R., 2005. Coccidioidomycosis—a fungal disease of the Americas. PLoS Med., 2(1):e2.

[9]Indhirajanti, S., Maartense, E., Posthuma, E.F., Pannekoek, B.J., Vreede, R.W., 2009. Pulmonary coccidioidomycosis: import illness and the importance of travel history. Neth. J. Med., 67(10):353-355.

[10]Jaroszewski, D.E., Halabi, W.J., Blair, J.E., Coakley, B.J., Wong, R.K., Parish, J.M., Vaszar, L.T., Kusne, S., Vikram, H.R., DeValeria, P.A., et al., 2009. Surgery for pulmonary coccidioidomycosis: a 10-year experience. Ann. Thorac. Surg., 88(6):1765-1772.

[11]Kishi, K., Fujii, T., Takaya, H., Miyamoto, A., Kurosaki, A., Kohno, T., Yoshimura, K., 2008. Pulmonary coccidioidomycosis found in healthy Japanese individuals. Respirology, 13(2):252-256.

[12]Kwok, H.K., Chan, J.W., Li, I.W., Chu, S.Y., Lam, C.W., 2009. Coccidioidomycosis as a rare cause of pneumonia in non-endemic areas: a short exposure history should not be ignored. Respirology, 14(4):617-620.

[13]Lan, F., Tong, Y.Z., Huang, H., Xiong, W.N., Xu, Y.J., Xiong, S.D., 2010. Primary pulmonary coccidioidomycosis in China. Respirology, 15(4):722-725.

[14]Laniado-Laborin, R., 2007. Expanding understanding of epidemiology of coccidioidomycosis in the western hemisphere. Ann. N. Y. Acad. Sci., 1111(1):19-34.

[15]Lee, C.H., Wilcox, L., Chorneyko, K., McIvor, A., 2008. Coccidioides immitis: two cases of misidentified mycosis. Can. Respir. J., 15(7):377-379.

[16]Saubolle, M.A., McKellar, P.P., Sussland, D., 2007. Epidemiologic, clinical, and diagnostic aspects of coccidioidomycosis. J. Clin. Microbiol., 45(1):26-30.

[17]Taxy, J.B., Kodros, S., 2005. Musculoskeletal coccidioidomycosis: unusual sites of disease in a nonendemic area. Am. J. Clin. Pathol., 124(5):693-696.

[18]Verghese, S., Arjundas, D., Krishnakumar, K.C., Padmaja, P., Elizabeth, D., Padhye, A.A., Warnock, D.W., 2002. Coccidioidomycosis in India: report of a second imported case. Med. Mycol., 40(3):307-309.

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2011-04-06 23:08:18

nice work

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