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CLC number: R657.3

On-line Access: 2011-05-06

Received: 2011-02-27

Revision Accepted: 2011-03-29

Crosschecked: 2011-03-11

Cited: 11

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Journal of Zhejiang University SCIENCE B 2011 Vol.12 No.5 P.357-364


Value of T-tube in biliary tract reconstruction during orthotopic liver transplantation: a meta-analysis

Author(s):  Wei-dong Huang, Jiu-kun Jiang, Yuan-qiang Lu

Affiliation(s):  Department of Emergency, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China

Corresponding email(s):   luyuanqiang@yahoo.cn

Key Words:  Liver transplantation, Drainage, Biliary tract, Meta-analysis, T-tube

Wei-dong Huang, Jiu-kun Jiang, Yuan-qiang Lu. Value of T-tube in biliary tract reconstruction during orthotopic liver transplantation: a meta-analysis[J]. Journal of Zhejiang University Science B, 2011, 12(5): 357-364.

@article{title="Value of T-tube in biliary tract reconstruction during orthotopic liver transplantation: a meta-analysis",
author="Wei-dong Huang, Jiu-kun Jiang, Yuan-qiang Lu",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Value of T-tube in biliary tract reconstruction during orthotopic liver transplantation: a meta-analysis
%A Wei-dong Huang
%A Jiu-kun Jiang
%A Yuan-qiang Lu
%J Journal of Zhejiang University SCIENCE B
%V 12
%N 5
%P 357-364
%@ 1673-1581
%D 2011
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1100054

T1 - Value of T-tube in biliary tract reconstruction during orthotopic liver transplantation: a meta-analysis
A1 - Wei-dong Huang
A1 - Jiu-kun Jiang
A1 - Yuan-qiang Lu
J0 - Journal of Zhejiang University Science B
VL - 12
IS - 5
SP - 357
EP - 364
%@ 1673-1581
Y1 - 2011
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1100054

Objective: To compare biliary complications after biliary tract reconstruction with or without t-tube in orthotopic liver transplantation. Methods: Randomized control trials (RCTs) and comparative studies were identified by a computerized literature search of the Cochrane Library, MEDLINE (1966/1–2010/4), Scopus (1980/1–2010/4), ClinicalTrials.gov (2010/4), the Cochrane Hepato-Biliary Group Controlled Trials Register, and the Cochrane Central Register of Controlled Trials. Studies and data were extracted and assessed independently. Dichotomous outcomes were reported as odds ratios (ORs) and weighted mean difference with 95% confidence intervals (CI). Results: Five RCTs and eight comparative studies with a total of 1 608 subjects were identified. The data showed that the operation with t-tube had better outcomes for duct stenosis (P=0.01, OR=0.45, 95% CI 0.24–0.85). The operations with or without t-tube had equivalent outcomes as follows: overall biliary complications (P=0.85, OR=1.15, 95% CI 0.28–4.72), bile leaks (P=0.38, OR=0.75, 95% CI 0.39–1.42), and cholangitis (P=0.24, OR=4.64, 95% CI 0.36–60.62). These results were strengthened by the analysis of all thirteen non-randomized and randomized studies. Conclusions: Our systematic review and meta-analysis suggest that the insertion of a t-tube reduces the incidence of biliary stenosis without increasing the incidence of other biliary complications.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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