Full Text:   <2585>

CLC number: R542.5

On-line Access: 2011-08-02

Received: 2011-07-04

Revision Accepted: 2011-07-11

Crosschecked: 2011-07-06

Cited: 6

Clicked: 5009

Citations:  Bibtex RefMan EndNote GB/T7714

-   Go to

Article info.
Open peer comments

Journal of Zhejiang University SCIENCE B 2011 Vol.12 No.8 P.633-637


MitraClip: a novel percutaneous approach to mitral valve repair

Author(s):  Hasan Jilaihawi, Asma Hussaini, Saibal Kar

Affiliation(s):  Cardiovascular Interventional Center, Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA

Corresponding email(s):   karsk@cshs.org

Key Words:  MitraClip, Mitral valve, Mitral regurgitation

Hasan Jilaihawi, Asma Hussaini, Saibal Kar. MitraClip: a novel percutaneous approach to mitral valve repair[J]. Journal of Zhejiang University Science B, 2011, 12(8): 633-637.

@article{title="MitraClip: a novel percutaneous approach to mitral valve repair",
author="Hasan Jilaihawi, Asma Hussaini, Saibal Kar",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T MitraClip: a novel percutaneous approach to mitral valve repair
%A Hasan Jilaihawi
%A Asma Hussaini
%A Saibal Kar
%J Journal of Zhejiang University SCIENCE B
%V 12
%N 8
%P 633-637
%@ 1673-1581
%D 2011
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1101009

T1 - MitraClip: a novel percutaneous approach to mitral valve repair
A1 - Hasan Jilaihawi
A1 - Asma Hussaini
A1 - Saibal Kar
J0 - Journal of Zhejiang University Science B
VL - 12
IS - 8
SP - 633
EP - 637
%@ 1673-1581
Y1 - 2011
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1101009

As life expectancy increases, valvular heart disease is becoming more common. Management of heart disease and primarily valvular heart disease is expected to represent a significant proportion of healthcare provided to the elderly population. Recent years have brought a progression of surgical treatments toward less invasive strategies. This has given rise to percutaneous approaches for the correction of valvular heart disease. Percutaneous mitral valve repair using the mitraClip system (Abbott Vascular, Santa Clara, CA, USA) creates a double orifice and has been successfully used in selected patients with mitral regurgitation. We review the rationale, procedural aspects, and clinical data thus far available for the mitraClip approach to mitral regurgitation.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


[1]Alfieri, O., Maisano, F., de Bonis, M., Stefano, P.L., Torracca, L., Oppizzi, M., La Canna, G., 2001. The double-orifice technique in mitral valve repair: a simple solution for complex problems. J. Thorac. Cardiovasc. Surg., 122(4):674-681.

[2]Carabello, B.A., 2008. The current therapy for mitral regurgitation. J. Am. Coll. Cardiol., 52(5):319-326.

[3]Enriquez-Sarano, M., Akins, C.W., Vahanian, A., 2009. Mitral regurgitation. Lancet, 373(9672):1382-1394.

[4]Fedak, P.W., McCarthy, P.M., Bonow, R.O., 2008. Evolving concepts and technologies in mitral valve repair. Circulation, 117(7):963-974.

[5]Feldman, T., Kar, S., Rinaldi, M., Fail, P., Hermiller, J., Smalling, R., Whitlow, P.L., Gray, W., Low, R., Herrmann, H.C., et al., 2009. Percutaneous mitral repair with the MitraClip system: safety and midterm durability in the initial EVEREST (Endovascular Valve Edge-to-Edge REpair Study) cohort. J. Am. Coll. Cardiol., 54(8):686-694.

[6]Feldman, T., Foster, E., Glower, D.G., Kar, S., Rinaldi, M.J., Fail, P.S., Smalling, R.W., Siegel, R., Rose, G.A., Engeron, E., et al., 2011. Percutaneous repair or surgery for mitral regurgitation. N. Engl. J. Med., 364(15):1395-1406.

[7]Franzen, O., Baldus, S., Rudolph, V., Meyer, S., Knap, M., Koschyk, D., Treede, H., Barmeyer, A., Schofer, J., Costard-Jäckle, A., et al., 2010. Acute outcomes of MitraClip therapy for mitral regurgitation in high-surgical-risk patients: emphasis on adverse valve morphology and severe left ventricular dysfunction. Eur. Heart J., 31(11):1373-1381.

[8]Franzen, O., van der Heyden, J., Baldus, S., Schlüter, M., Schillinger, W., Butter, C., Hoffmann, R., Corti, R., Pedrazzini, G., Swaans, M.L., et al., 2011. MitraClip® therapy in patients with end-stage systolic heart failure. Eur. J. Heart Fail., 13(5):569-576.

[9]Herrmann, H.C., Kar, S., Siegel, R., Fail, P., Loghin, C., Lim, S., Hahn, R., Rogers, J.H., Bommer, W.J., Wang, A., et al., 2009. Effect of percutaneous mitral repair with the MitraClip device on mitral valve area and gradient. EuroIntervention, 4(4):437-442.

[10]Hussaini, A., Kar, S., 2010. Percutaneous mitral valve repair: potential in heart failure management. Curr. Heart Fail. Rep., 7:22-26.

[11]Kar, S., Feldman, T.E., St. Goar, F., 2008. Mitral valve repair using the MitraClip: from concept to reality. Cardiac Interventions Today, p.39-45.

[12]Kar, S., Foster, E., Glower, D., Feldman, T., 2011. MitraClip therapy demonstrates continued clinical benefit and favorable left ventricular remodeling at two years in high risk surgical patients with significant mitral regurgitation: analysis of the everest II high risk registry. J. Am. Coll. Cardiol., 57:1308.

[13]Tamburino, C., Ussia, G.P., Maisano, F., Capodanno, D., La Canna, G., Scandura, S., Colombo, A., Giacomini, A., Michev, I., Mangiafico, S., et al., 2010. Percutaneous mitral valve repair with the MitraClip system: acute results from a real world setting. Eur. Heart J., 31(11):1382-1389.

Open peer comments: Debate/Discuss/Question/Opinion


Please provide your name, email address and a comment

Journal of Zhejiang University-SCIENCE, 38 Zheda Road, Hangzhou 310027, China
Tel: +86-571-87952783; E-mail: cjzhang@zju.edu.cn
Copyright © 2000 - 2024 Journal of Zhejiang University-SCIENCE