CLC number: S852.65
On-line Access: 2024-08-27
Received: 2023-10-17
Revision Accepted: 2024-05-08
Crosschecked: 2017-05-10
Cited: 0
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Jiang-bing Shuai, Lu-huan Li, Ai-yun Li, Yong-qiang He, Xiao-feng Zhang. Full genome analysis of swine genotype 3 hepatitis E virus isolated from eastern China[J]. Journal of Zhejiang University Science B, 2017, 18(6): 549-554.
@article{title="Full genome analysis of swine genotype 3 hepatitis E virus isolated from eastern China",
author="Jiang-bing Shuai, Lu-huan Li, Ai-yun Li, Yong-qiang He, Xiao-feng Zhang",
journal="Journal of Zhejiang University Science B",
volume="18",
number="6",
pages="549-554",
year="2017",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B1600419"
}
%0 Journal Article
%T Full genome analysis of swine genotype 3 hepatitis E virus isolated from eastern China
%A Jiang-bing Shuai
%A Lu-huan Li
%A Ai-yun Li
%A Yong-qiang He
%A Xiao-feng Zhang
%J Journal of Zhejiang University SCIENCE B
%V 18
%N 6
%P 549-554
%@ 1673-1581
%D 2017
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1600419
TY - JOUR
T1 - Full genome analysis of swine genotype 3 hepatitis E virus isolated from eastern China
A1 - Jiang-bing Shuai
A1 - Lu-huan Li
A1 - Ai-yun Li
A1 - Yong-qiang He
A1 - Xiao-feng Zhang
J0 - Journal of Zhejiang University Science B
VL - 18
IS - 6
SP - 549
EP - 554
%@ 1673-1581
Y1 - 2017
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1600419
Abstract: Hepatitis E is believed to occur in both endemic and sporadic forms in developing countries, which causes a major public health problem in Asia and Africa (Meng, 2010; Wang et al., 2016a). Recent studies have documented that the disease is also endemic in many industrialized countries (Wenzel et al., 2011). The causative agent, hepatitis E virus (HEV), belonging to the genus Orthohepevirus, is a non-enveloped RNA virus with a single-stranded, positive-sense genome of approximately 7.2 kb (Smith et al., 2014). The genome consists of a short 5' un-translated region (UTR), three open reading frames (ORFs), and a 3' UTR containing a poly(A) tail (Meng, 2011). Four recognized major genotypes of HEV are identified: genotype 1 (Asian and African strains), genotype 2 (a Mexican strain), genotype 3 (primarily from America and Europe, and some Asian countries), and genotype 4 (mainly Asian strains) (Smith et al., 2016). Previous study revealed that HEV genotype 4 is the dominant zoonotic HEV genotype in China (Wang et al., 2016a). However, infections with HEV 3 have been found more commonly in recent years in China (Liu et al., 2012; Zhang et al., 2013). To date, only one full genome of Chinese swine genotype 3 HEV strain from Shanghai has been documented (Si et al., 2009). We report here the first full genome sequence of a genotype 3 swine HEV strain from Zhejiang, China.
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