Full Text:   <2226>

Summary:  <1594>

CLC number: Q39

On-line Access: 2019-05-15

Received: 2019-01-24

Revision Accepted: 2019-04-16

Crosschecked: 2019-05-03

Cited: 0

Clicked: 3858

Citations:  Bibtex RefMan EndNote GB/T7714


Ai-fu Lin


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Journal of Zhejiang University SCIENCE B 2019 Vol.20 No.6 P.488-495


Exosomal long non-coding RNAs: biological properties and therapeutic potential in cancer treatment

Author(s):  Jie Luo, Yan Xiong, Pei-Fen Fu, En-Chun Li, Lei Qu, Xiao Fan, Zhi-Jian Cai, Ai-Fu Lin

Affiliation(s):  Department of Gynecology, Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China; more

Corresponding email(s):   linaifu@zju.edu.cn, caizj@zju.edu.cn

Key Words:  Exosome, Long non-coding RNA (lncRNA), Biosynthesis, Biomarker, Drug resistance

Jie Luo, Yan Xiong, Pei-Fen Fu, En-Chun Li, Lei Qu, Xiao Fan, Zhi-Jian Cai, Ai-Fu Lin. Exosomal long non-coding RNAs: biological properties and therapeutic potential in cancer treatment[J]. Journal of Zhejiang University Science B, 2019, 20(6): 488-495.

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journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

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%T Exosomal long non-coding RNAs: biological properties and therapeutic potential in cancer treatment
%A Jie Luo
%A Yan Xiong
%A Pei-Fen Fu
%A En-Chun Li
%A Lei Qu
%A Xiao Fan
%A Zhi-Jian Cai
%A Ai-Fu Lin
%J Journal of Zhejiang University SCIENCE B
%V 20
%N 6
%P 488-495
%@ 1673-1581
%D 2019
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1900039

T1 - Exosomal long non-coding RNAs: biological properties and therapeutic potential in cancer treatment
A1 - Jie Luo
A1 - Yan Xiong
A1 - Pei-Fen Fu
A1 - En-Chun Li
A1 - Lei Qu
A1 - Xiao Fan
A1 - Zhi-Jian Cai
A1 - Ai-Fu Lin
J0 - Journal of Zhejiang University Science B
VL - 20
IS - 6
SP - 488
EP - 495
%@ 1673-1581
Y1 - 2019
PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.B1900039

exosomes and long non-coding RNAs (lncRNAs) are emerging as important elements contributing to a more comprehensive understanding of cancer development and progression. The discovery of lncRNAs in exosomes further indicates their bona fide biological functional roles in cancer development and drug resistance. In this review, we describe the biogenesis of exosomes and summarize the function of exosomal lncRNAs in the field of cancer research. These findings strikingly advance current knowledge of exosomal lncRNAs and suggest that they may be promising diagnostic biomarkers and therapeutic targets for cancer.



Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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