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Received: 2023-01-29

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Xi-Ping Zhang


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Journal of Zhejiang University SCIENCE B 2023 Vol.24 No.12 P.1123-1140


Roles of lncRNA in the diagnosis and prognosis of triple-negative breast cancer

Author(s):  Qiuhui YANG, Yeqin FU, Jiaxuan WANG, Hongjian YANG, Xiping ZHANG

Affiliation(s):  Department of Breast Surgery, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou 310022, China; more

Corresponding email(s):   zxp99688@sina.com

Key Words:  Triple-negative breast cancer (TNBC), Long non-coding RNA (lncRNA), Diagnosis, Prognosis, Chemotherapy resistance

Qiuhui YANG, Yeqin FU, Jiaxuan WANG, Hongjian YANG, Xiping ZHANG. Roles of lncRNA in the diagnosis and prognosis of triple-negative breast cancer[J]. Journal of Zhejiang University Science B, 2023, 24(12): 1123-1140.

@article{title="Roles of lncRNA in the diagnosis and prognosis of triple-negative breast cancer",
author="Qiuhui YANG, Yeqin FU, Jiaxuan WANG, Hongjian YANG, Xiping ZHANG",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Roles of lncRNA in the diagnosis and prognosis of triple-negative breast cancer
%A Qiuhui YANG
%A Yeqin FU
%A Jiaxuan WANG
%A Hongjian YANG
%A Xiping ZHANG
%J Journal of Zhejiang University SCIENCE B
%V 24
%N 12
%P 1123-1140
%@ 1673-1581
%D 2023
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2300067

T1 - Roles of lncRNA in the diagnosis and prognosis of triple-negative breast cancer
A1 - Qiuhui YANG
A1 - Yeqin FU
A1 - Jiaxuan WANG
A1 - Hongjian YANG
A1 - Xiping ZHANG
J0 - Journal of Zhejiang University Science B
VL - 24
IS - 12
SP - 1123
EP - 1140
%@ 1673-1581
Y1 - 2023
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B2300067

Breast cancer is a malignant tumor that seriously endangers women’s lives. The prognosis of breast cancer patients differs among molecular types. Compared with other subtypes, triple-negative breast cancer (TNBC) has been a research hotspot in recent years because of its high degree of malignancy, strong invasiveness, rapid progression, easy of recurrence, distant metastasis, poor prognosis, and high mortality. Many studies have found that long non-coding RNA (lncRNA) plays an important role in the occurrence, proliferation, migration, recurrence, chemotherapy resistance, and other characteristics of TNBC. Some lncRNAs are expected to become biomarkers in the diagnosis and prognosis of TNBC, and even new targets for its treatment. Based on a PubMed literature search, this review summarizes the progress in research on lncRNAs in TNBC and discusses their roles in TNBC diagnosis, prognosis, and chemotherapy with the hope of providing help for future research.




Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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