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On-line Access: 2024-08-27

Received: 2023-10-17

Revision Accepted: 2024-05-08

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Citations:  Bibtex RefMan EndNote GB/T7714

 ORCID:

Yuan-qiang Lu

https://orcid.org/0000-0002-9057-4344

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Journal of Zhejiang University SCIENCE B 2021 Vol.22 No.3 P.248-252

http://doi.org/10.1631/jzus.B2000601


Peripheral nerve injury in patients exposed to n-hexane: an analysis of eight cases


Author(s):  Xiaping ZHANG, Yaling TONG, Yuanqiang LU

Affiliation(s):  Department of Emergency Medicine, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China; more

Corresponding email(s):   luyuanqiang@zju.edu.cn

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Xiaping ZHANG, Yaling TONG, Yuanqiang LU. Peripheral nerve injury in patients exposed to n-hexane: an analysis of eight cases[J]. Journal of Zhejiang University Science B, 2021, 22(3): 248-252.

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T1 - Peripheral nerve injury in patients exposed to n-hexane: an analysis of eight cases
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DOI - 10.1631/jzus.B2000601


Abstract: 
Poisoning is often characterized by the acute onset, rapid progress, or specific manifestations of pathological symptoms, such as pulmonary fibrosis due to paraquat poisoning or high mortality arising from dinitrophenol intoxication (Jiang et al., 2016; Wang et al., 2017; Feng et al., 2018; Lu, 2018; Xu and Lu, 2019). Unlike general poisoning, however, the manifestation of n-hexane intoxication is subacute, and its clinical symptoms are dormant, and thus the provision of a timely and correct diagnosis is often difficult.

正己烷中毒致周围神经病变的八例临床分析

目的:探讨亚急性正己烷中毒引起的周围神经病的临床特征、诊断和及治疗。
创新点:亚急性正己烷中毒主要表现为多发性周围神经病,其特点为隐匿性、潜伏期较长、易造成误诊。根据我们一系列病例分析,我们建议医生在遇到有运动和感觉功能障碍临床表现的患者时,除了考虑神经系统疾病外,还应考虑正己烷中毒的可能性。此外,病人的职业也是正确诊断不可忽视的信息。
方法:回顾分析职业性亚急性正己烷中毒患者八例,大多表现为行动无力和四肢麻木。所有患者都曾在当地医院接受过治疗,而误诊率高达87.5%(7/8)。因正己烷无特殊解毒剂,通过皮质激素、神经营养药物等支持性治疗,以及康复训练和针灸治疗后,患者大多预后良好,神经电生理有所改善。
结论:正己烷中毒可引起周围神经受损症状,患者电生理表现明显异常,经积极治疗后,其临床预后良好。

关键词:正己烷;中毒;神经肌电图

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference

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