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On-line Access: 2024-02-01

Received: 2023-08-17

Revision Accepted: 2023-11-08

Crosschecked: 2024-02-02

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Xiaotong ZHANG


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Journal of Zhejiang University SCIENCE B 2024 Vol.25 No.2 P.168-180


A proton birdcage coil integrated with interchangeable single loops for multi-nuclear MRI/MRS

Author(s):  Yi ZHANG, Zhiyan QUAN, Feiyang LOU, Yujiao FANG, Garth J. THOMPSON, Gao CHEN, Xiaotong ZHANG

Affiliation(s):  Department of Neurosurgery, the Second Affiliated Hospital, School of Medicine, Zhejiang University,Hangzhou310009,China; more

Corresponding email(s):   d-chengao@zju.edu.cn, zhangxiaotong@zju.edu.cn

Key Words:  Energy metabolism, Magnetic resonance imaging (MRI), Magnetic resonance spectroscopy (MRS), Multi-nuclear, Radiofrequency coil, Three-dimensional (3D) printing

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Yi ZHANG, Zhiyan QUAN, Feiyang LOU, Yujiao FANG, Garth J. THOMPSON, Gao CHEN, Xiaotong ZHANG. A proton birdcage coil integrated with interchangeable single loops for multi-nuclear MRI/MRS[J]. Journal of Zhejiang University Science B, 2024, 25(2): 168-180.

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author="Yi ZHANG, Zhiyan QUAN, Feiyang LOU, Yujiao FANG, Garth J. THOMPSON, Gao CHEN, Xiaotong ZHANG",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

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%A Zhiyan QUAN
%A Feiyang LOU
%A Yujiao FANG
%A Xiaotong ZHANG
%J Journal of Zhejiang University SCIENCE B
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%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2300587

T1 - A proton birdcage coil integrated with interchangeable single loops for multi-nuclear MRI/MRS
A1 - Zhiyan QUAN
A1 - Feiyang LOU
A1 - Yujiao FANG
A1 - Garth J. THOMPSON
A1 - Gao CHEN
A1 - Xiaotong ZHANG
J0 - Journal of Zhejiang University Science B
VL - 25
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%@ 1673-1581
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PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.B2300587

energy metabolism is fundamental for life. It encompasses the utilization of carbohydrates, lipids, and proteins for internal processes, while aberrant energy metabolism is implicated in many diseases. In the present study, using three-dimensional (3D) printing from polycarbonate via fused deposition modeling, we propose a multi-nuclear radiofrequency (RF) coil design with integrated1H birdcage and interchangeable X-nuclei (2H,13C,23Na, and31P) single-loop coils for magnetic resonance imaging (MRI)/magnetic resonance spectroscopy (MRS). The single-loop coil for each nucleus attaches to an arc bracket that slides unrestrictedly along the birdcage coil inner surface, enabling convenient switching among various nuclei and animal handling. Compared to a commercial1H birdcage coil, the proposed1H birdcage coil exhibited superior signal-excitation homogeneity and imaging signal-to-noise ratio (SNR). For X-nuclei study, prominent peaks in spectroscopy for phantom solutions showed excellent SNR, and the static and dynamic peaks of in vivo spectroscopy validated the efficacy of the coil design in structural imaging and energy metabolism detection simultaneously.


张怡1,2,3,全枝艳3,4,楼飞洋3,4,5,方玉娇6,Garth J. THOMPSON6,陈高1,2,张孝通1,2,3,4,5,7


Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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