Full Text:
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CLC number:
On-line Access: 2025-10-27
Received: 2025-04-12
Revision Accepted: 2025-07-22
Crosschecked: 0000-00-00
Cited: 0
Clicked: 10
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Development of novel microtubular ionic actuators for endovascular navigation
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Qingsong He (???), Siyuan Liu (???), Xiaofang Liu (???), Weixiang Gao (???), Zhihao Lv (???), Xin Shen (??), Jinjun Duan (???), Yunfei Han (???), Jianfeng Zhao (???), Ying Hu (??), Wenqi Liu (???), Fengjiang Zhan (???), Longfei Chang (???), Tao Wang (??), Yuze Ye (???), Qiyun Zhong (???), Xinyu Lu (???), Weiming Xu (???), Yefu Wang (???), Yang Gu (??), Chenchu Zhang (???), Dong Wu (??) & Yong Li (??) . Development of novel microtubular ionic actuators for endovascular navigation[J]. Journal of Zhejiang University Science D, 2025, 8(6): 948-961.
@article{title="Development of novel microtubular ionic actuators for endovascular
navigation",
author="Qingsong He (???), Siyuan Liu (???), Xiaofang Liu (???), Weixiang Gao (???), Zhihao Lv (???), Xin Shen (??), Jinjun Duan (???), Yunfei Han (???), Jianfeng Zhao (???), Ying Hu (??), Wenqi Liu (???), Fengjiang Zhan (???), Longfei Chang (???), Tao Wang (??), Yuze Ye (???), Qiyun Zhong (???), Xinyu Lu (???), Weiming Xu (???), Yefu Wang (???), Yang Gu (??), Chenchu Zhang (???), Dong Wu (??) & Yong Li (??) ",
journal="Journal of Zhejiang University Science D",
volume="8",
number="6",
pages="948-961",
year="2025",
publisher="Zhejiang University Press & Springer",
doi="10.1631/bdm.2500183"
}
%0 Journal Article
%T Development of novel microtubular ionic actuators for endovascular
navigation
%A Qingsong He (???)
%A Siyuan Liu (???)
%A Xiaofang Liu (???)
%A Weixiang Gao (???)
%A Zhihao Lv (???)
%A Xin Shen (??)
%A Jinjun Duan (???)
%A Yunfei Han (???)
%A Jianfeng Zhao (???)
%A Ying Hu (??)
%A Wenqi Liu (???)
%A Fengjiang Zhan (???)
%A Longfei Chang (???)
%A Tao Wang (??)
%A Yuze Ye (???)
%A Qiyun Zhong (???)
%A Xinyu Lu (???)
%A Weiming Xu (???)
%A Yefu Wang (???)
%A Yang Gu (??)
%A Chenchu Zhang (???)
%A Dong Wu (??) & Yong Li (??)
%J Journal of Zhejiang University SCIENCE D
%V 8
%N 6
%P 948-961
%@ 1869-1951
%D 2025
%I Zhejiang University Press & Springer
%DOI 10.1631/bdm.2500183
TY - JOUR
T1 - Development of novel microtubular ionic actuators for endovascular
navigation
A1 - Qingsong He (???)
A1 - Siyuan Liu (???)
A1 - Xiaofang Liu (???)
A1 - Weixiang Gao (???)
A1 - Zhihao Lv (???)
A1 - Xin Shen (??)
A1 - Jinjun Duan (???)
A1 - Yunfei Han (???)
A1 - Jianfeng Zhao (???)
A1 - Ying Hu (??)
A1 - Wenqi Liu (???)
A1 - Fengjiang Zhan (???)
A1 - Longfei Chang (???)
A1 - Tao Wang (??)
A1 - Yuze Ye (???)
A1 - Qiyun Zhong (???)
A1 - Xinyu Lu (???)
A1 - Weiming Xu (???)
A1 - Yefu Wang (???)
A1 - Yang Gu (??)
A1 - Chenchu Zhang (???)
A1 - Dong Wu (??) & Yong Li (??)
J0 - Journal of Zhejiang University Science D
VL - 8
IS - 6
SP - 948
EP - 961
%@ 1869-1951
Y1 - 2025
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/bdm.2500183
Abstract: Minimally invasive interventional surgery techniques using guidewire-based catheters are widely adopted to treat vascular
diseases. However, commonly used interventional catheters lack active guidance. The use of guidewires is associated with
risks, including increased exposure to X-rays and potential vascular damage during withdrawal from complex vessels.
Herein, we developed sub-millimeter microtubular ionic actuators (0.60.8 mm outer diameter) integrated into steerable inter
ventional catheters. These actuators can generate large deformations (>10 mm) under 7 V direct current due to enhanced ion
migration, enabling precise navigation without the need for guidewires. The designed catheters achieved active bending and
accurate positioning in complex arterial vascular branches within a human model. They were also able to navigate within dif
ferent arterial locations (e.g., the innominate, subclavian, and carotid arteries) in pigs without the use of guidewires, and even
access the ventricle and deliver contrast medium, indicating their great potential for future endovascular therapy.
Open peer comments: Debate/Discuss/Question/Opinion
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