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Abstract: 4a8b>28arbutin%4a8b>29&ck%5B%5D=abstract&ck%5B%5D=keyword'>4a8b>2f4a8b>arbutin was synthesized from glucose by two-step reaction below: (a) 4a8b>2,4a8b>3,4,6-tetra-O-acetyl-α-D-glucosyl chloride or bromide was prepared by glucose and acetyl halide (chloride or bromide). (b) 4a8b>2,4a8b>3,4,6-tetra-O-acetyl-α-D-glucosyl halide (Cl, br) reacted with hydroquinone, methanol as solvent at pH=9.5~10.0.

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