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Abstract: The incidence of "three highs", referring to hyperglycemia, hypertension, and hyperlipidemia, has been increasing rapidly all over the world (Dey and Raj, 2013; Gao et al., 2019). These illnesses may be attributed to the perturbations of blood metabolites which are small molecules within biofluids (Patil et al., 2018). Among them, the presence of cholesterol and glucose in blood at abnormal levels highly increases the risk of cardiac and brain vascular diseases, and diabetes (Li et al., 2019). Furthermore, it has been confirmed that high glucose concentration is one of the main causes of atherosclerosis, by causing the accumulation of cholesterol in macrophages (Henry et al., 2002). Therefore, for early diagnosis of these diseases, the development of a low-cost, simple, and efficient strategy for simultaneous, accurate, and rapid detection of multiple metabolites is greatly needed for on-site disease monitoring in-home healthcare.

自支撑MXene/壳聚糖/Cu₂O电极：一种高效的同时测定葡萄糖和胆固醇的无酶生物传感器

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