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Abstract: Aortic stenosis (AS) is a progressive heart valve disease occurring predominantly in older patients. According to a survey in a western country, the prevalence of AS is nearly 6.4% in patients over 75 years old (Carabello and Paulus, 2009). Transcatheter aortic valve replacement (TAVR) is an alternative method for AS patients. Previous studies have described how up to 66% of TAVR patients have concomitant baseline kidney dysfunction (Ferro et al., 2015; Gargiulo et al., 2015). The majority of patients can benefit from the TAVR procedure with the recovery of kidney function. The TAVR procedure releases the obstruction of the left ventricle caused by severe AS, and the increased cardiac output may be reasonably responsible for recovery of the kidney function (Ewe et al., 2010; Dauerman et al., 2016). Kidney dysfunction is most commonly attributed to diabetes and hypertension (HTN) (Chen et al., 2019). A few studies have reported kidney function change after TAVR in baseline chronic kidney disease (CKD) patients (Beohar et al., 2017; Azarbal et al., 2019; Okoh et al., 2019). However, no study has focused on kidney function change after TAVR in the diabetic or hypertensive population. Therefore, we aimed to investigate kidney function change during the TAVR procedure in patients with diabetes mellites (DM) and/or HTN.

糖尿病和（或）高血压患者经导管主动脉瓣置换术后肾功能改变研究

[1]AbueloJG, 2007. Normotensive ischemic acute renal failure. N Engl J Med, 357(8):797-805.

[2]AzarbalA, MalenkaDJ, HuangYL, et al., 2019. Recovery of kidney dysfunction after transcatheter aortic valve implantation (from the Northern New England Cardiovascular Disease Study Group). Am J Cardiol, 123(3):426-433.

[3]BanovicM, AthithanL, McCannGP, 2019. Aortic stenosis and diabetes mellitus: an ominous combination. Diabetes Vasc Dis Res, 16(4):310-323.

[4]BeoharN, DoshiD, ThouraniV, et al., 2017. Association of transcatheter aortic valve replacement with 30-day renal function and 1-year outcomes among patients presenting with compromised baseline renal function: experience from the PARTNER 1 trial and registry. JAMA Cardiol, 2(7):742-749.

[5]CarabelloBA, PaulusWJ, 2009. Aortic stenosis. Lancet, 373(9667):956-966.

[6]ChenTK, KnicelyDH, GramsME, 2019. Chronic kidney disease diagnosis and management: a review. JAMA, 322(13):1294-1304.

[7]DauermanHL, ReardonMJ, PopmaJJ, et al., 2016. Early recovery of left ventricular systolic function after CoreValve transcatheter aortic valve replacement. Circ Cardiovasc Interv, 9(6):e003425.

[8]EweSH, MarsanNA, PepiM, et al., 2010. Impact of left ventricular systolic function on clinical and echocardiographic outcomes following transcatheter aortic valve implantation for severe aortic stenosis. Am Heart J, 160(6):1113-1120.

[9]FanJQ, FangX, LiuCH, et al., 2020. Brain injury after transcatheter replacement of bicuspid versus tricuspid aortic valves. J Am Coll Cardiol, 76(22):2579-2590.

[10]FerroCJ, ChueCD, BelderMA, et al., 2015. Impact of renal function on survival after transcatheter aortic valve implantation (TAVI): an analysis of the UK TAVI registry. Heart, 101(7):546-552.

[11]FischerUM, WeissenbergerWK, WartersRD, et al., 2002. Impact of cardiopulmonary bypass management on postcardiac surgery renal function. Perfusion, 17(6):401-406.

[12]GargiuloG, CapodannoD, SanninoA, et al., 2015. Moderate and severe preoperative chronic kidney disease worsen clinical outcomes after transcatheter aortic valve implantation: meta-analysis of 4992 patients. Circ Cardiovasc Interv, 8(2):e002220.

[13]KappeteinAP, HeadSJ, GénéreuxP, et al., 2012. Updated standardized endpoint definitions for transcatheter aortic valve implantation. J Am Coll Cardiol, 60(15):1438-1454.

[14]MinaGS, GillP, SolimanD, et al., 2017. Diabetes mellitus is associated with increased acute kidney injury and 1-year mortality after transcatheter aortic valve replacement: a meta-analysis. Clin Cardiol, 40(9):726-731.

[15]OkohAK, KambizK, UnnikrishnanD, et al., 2019. Effect of transcatheter aortic valve implantation on renal function in patients with previous renal dysfunction. Am J Cardiol, 124(1):85-89.

[16]RangaswamiJ, BhallaV, BlairJEA, et al., 2019. Cardiorenal syndrome: classification, pathophysiology, diagnosis, and treatment strategies: a scientific statement from the American Heart Association. Circulation, 139(16):e840-e878.

[17]RieckÅE, CramariucD, BomanK, et al., 2012. Hypertension in aortic stenosis implications for left ventricular structure and cardiovascular events. Hypertension, 60(1):90-97.

[18]SchewelD, ZavarehM, SchewelJ, et al., 2017. Impact of interaction of diabetes mellitus and impaired renal function on prognosis and the incidence of acute kidney injury in patients undergoing transcatheter aortic valve replacement (TAVR). Int J Cardiol, 232:147-154.

[19]ThongprayoonC, CheungpasitpornW, SrivaliN, et al., 2015. Acute kidney injury after transcatheter aortic valve replacement: a systematic review and meta-analysis. Am J Nephrol, 41(4-5):372-382.