CLC number:
On-line Access: 2022-05-13
Received: 2021-09-15
Revision Accepted: 2022-01-27
Crosschecked: 2022-05-13
Cited: 0
Clicked: 1519
Citations: Bibtex RefMan EndNote GB/T7714
Yuting XU, Li ZHANG, Dickson Kofi Wiredu OCANSEY, Bo WANG, Yilin HOU, Rong MEI, Yongmin YAN, Xu ZHANG, Zhaoyang ZHANG, Fei MAO. HucMSC-Ex alleviates inflammatory bowel disease via the lnc78583-mediated miR3202/HOXB13 pathway[J]. Journal of Zhejiang University Science B, 2022, 23(5): 423-431.
@article{title="HucMSC-Ex alleviates inflammatory bowel disease via the lnc78583-mediated miR3202/HOXB13 pathway",
author="Yuting XU, Li ZHANG, Dickson Kofi Wiredu OCANSEY, Bo WANG, Yilin HOU, Rong MEI, Yongmin YAN, Xu ZHANG, Zhaoyang ZHANG, Fei MAO",
journal="Journal of Zhejiang University Science B",
volume="23",
number="5",
pages="423-431",
year="2022",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B2100793"
}
%0 Journal Article
%T HucMSC-Ex alleviates inflammatory bowel disease via the lnc78583-mediated miR3202/HOXB13 pathway
%A Yuting XU
%A Li ZHANG
%A Dickson Kofi Wiredu OCANSEY
%A Bo WANG
%A Yilin HOU
%A Rong MEI
%A Yongmin YAN
%A Xu ZHANG
%A Zhaoyang ZHANG
%A Fei MAO
%J Journal of Zhejiang University SCIENCE B
%V 23
%N 5
%P 423-431
%@ 1673-1581
%D 2022
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2100793
TY - JOUR
T1 - HucMSC-Ex alleviates inflammatory bowel disease via the lnc78583-mediated miR3202/HOXB13 pathway
A1 - Yuting XU
A1 - Li ZHANG
A1 - Dickson Kofi Wiredu OCANSEY
A1 - Bo WANG
A1 - Yilin HOU
A1 - Rong MEI
A1 - Yongmin YAN
A1 - Xu ZHANG
A1 - Zhaoyang ZHANG
A1 - Fei MAO
J0 - Journal of Zhejiang University Science B
VL - 23
IS - 5
SP - 423
EP - 431
%@ 1673-1581
Y1 - 2022
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B2100793
Abstract: As a group of nonspecific inflammatory diseases affecting the intestine, inflammatory bowel disease (IBD) exhibits the characteristics of chronic recurring inflammation, and was proven to be increasing in incidence (Kaplan, 2015). IBD induced by genetic background, environmental changes, immune functions, microbial composition, and toxin exposures (Sasson et al., 2021) primarily includes ulcerative colitis (UC) and Crohn's disease (CD) with complicated clinical symptoms featured by abdominal pain, diarrhea, and even blood in stools (Fan et al., 2021; Huang et al., 2021). UC is mainly limited to the rectum and the colon, while CD usually impacts the terminal ileum and colon in a discontinuous manner (Ordás et al., 2012; Panés and Rimola, 2017). In recent years, many studies have suggested the lack of effective measures in the diagnosis and treatment of IBD, prompting an urgent need for new strategies to understand the mechanisms of and offer promising therapies for IBD.
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