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On-line Access: 2023-02-22
Received: 2022-06-25
Revision Accepted: 2022-12-23
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Performance of novel 3D printing tools in removing coronary-artery calcification tissue
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Chuhang Gao, Zhaoju Zhu, Zirui Huang, Liujing Chen, Lihong Lu, Mingcheng Fang, Yao Liu & Bingwei He. Performance of novel 3D printing tools in removing coronary-artery calcification tissue[J]. Journal of Zhejiang University Science D, 2023, 6(4): 390-404.
@article{title="Performance of novel 3D printing tools in removing coronary-artery
calcification tissue",
author="Chuhang Gao, Zhaoju Zhu, Zirui Huang, Liujing Chen, Lihong Lu, Mingcheng Fang, Yao Liu & Bingwei He",
journal="Journal of Zhejiang University Science D",
volume="6",
number="4",
pages="390-404",
year="2023",
publisher="Zhejiang University Press & Springer",
doi="10.1007/s42242-022-00228-w"
}
%0 Journal Article
%T Performance of novel 3D printing tools in removing coronary-artery
calcification tissue
%A Chuhang Gao
%A Zhaoju Zhu
%A Zirui Huang
%A Liujing Chen
%A Lihong Lu
%A Mingcheng Fang
%A Yao Liu & Bingwei He
%J Journal of Zhejiang University SCIENCE D
%V 6
%N 4
%P 390-404
%@ 1869-1951
%D 2023
%I Zhejiang University Press & Springer
%DOI 10.1007/s42242-022-00228-w
TY - JOUR
T1 - Performance of novel 3D printing tools in removing coronary-artery
calcification tissue
A1 - Chuhang Gao
A1 - Zhaoju Zhu
A1 - Zirui Huang
A1 - Liujing Chen
A1 - Lihong Lu
A1 - Mingcheng Fang
A1 - Yao Liu & Bingwei He
J0 - Journal of Zhejiang University Science D
VL - 6
IS - 4
SP - 390
EP - 404
%@ 1869-1951
Y1 - 2023
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1007/s42242-022-00228-w
Abstract: rotational atherectomy is an effective treatment for severe vascular calcification obstruction, and relies on high-speed grinding
(typically 130,000–210,000 r/min) with miniature grinding tools to remove calcified tissue and restore blood flow. However,
reports of intraoperative complications are common because of the grinding force, temperature, and debris directly acting on
the body during the grinding process, which can easily cause damage to patients. In this study, three novel grinding tools
were designed and fabricated and a series of experiments have been conducted to analyze the effects of tool geometry and
parameters on grinding performance, that is, force, temperature, and specimen surface morphology. The results show that
these tools can effectively remove simulated calcified tissue and that they have two motions, rotation and revolution, in the
tube. At higher rotational speeds, grinding force and temperature increase noticeably, while the amount of debris decreases
significantly. In addition, by observing the surface morphology of the specimens, we concluded that the material removal rate
per unit time is influenced by both rotational speed and tool geometry, and that high rotational speed and a rough tool surface
can improve the material removal rate efficiently.
本研究论文聚焦冠状动脉粥样硬化介入治疗，提出了三种适用于冠状动脉旋磨术的新型旋磨刀具。冠状动脉旋磨术（Coronary Rotational Atherectomy，CRA）作为一种治疗重度血管钙化阻塞的有效手段，主要依靠微小磨头在体内高速磨削以达到去除钙化组织并恢复血运的功效。但由于旋磨过程中旋磨力、温度以及碎屑直接作用于人体，容易造成机体损伤，因此关于术中并发症的报道屡见不鲜。针对旋磨术中存在的组织损伤问题，本文提出了三种新型旋磨刀具并搭建配套实验平台，分别使用四种转速80000、110000、140000、170000rpm进行旋磨实验，分析旋磨过程中旋磨刀具参数与旋磨参数对旋磨力、温度、磨削深度以及磨屑的影响，观察旋磨刀具运动轨迹以及旋磨后的试样磨损情况。实验结果表明：所设计的旋磨刀具均能够有效旋磨去除模拟钙化组织；旋磨刀具在管腔内存在自转与公转两种运动形式，运动速度取决于旋磨转速大小；随着旋磨转速的增大，旋磨力、旋磨温升、磨削深度显著增大而磨屑粒径明显减小。同时，通过观察试样表面形貌可以得到单位时间内材料去除率受到转速与刀具参数的影响，高转速与粗糙刀具表面都会使材料去除率得到提升。
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