Bio-Design and Manufacturing  2026 Vol.9 No.5 P.1049 - 1058

http://doi.org/10.1631/bdm.2600036


A dual-mode radiofrequency ablation catheter with advanced thermal sensing for saphenous and perforator vein insufficiency: a preclinical study on goats


Author(s):  Zheng Gu,Xiangman Zhang,Zhenying Guo,Zhenjie Liu

Affiliation(s):  1. Clinical Medical Engineering Department, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China more

Corresponding email(s):   lawson4001@zju.edu.cn

Key Words: 


Zheng Gu, Xiangman Zhang, Zhenying Guo, Zhenjie Liu. A dual-mode radiofrequency ablation catheter with advanced thermal sensing for saphenous and perforator vein insufficiency: a preclinical study on goats[J]. Journal of Zhejiang University Science D, 2026, 9(5): 1049 - 1058.

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author="Zheng Gu, Xiangman Zhang, Zhenying Guo, Zhenjie Liu",
journal="Journal of Zhejiang University Science D",
volume="9",
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pages="1049 - 1058",
year="2026",
publisher="Zhejiang University Press & Springer",
doi="10.1631/bdm.2600036"
}

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%A Zheng Gu
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%A Zhenying Guo
%A Zhenjie Liu
%J Journal of Zhejiang University SCIENCE D
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%I Zhejiang University Press & Springer
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T1 - A dual-mode radiofrequency ablation catheter with advanced thermal sensing for saphenous and perforator vein insufficiency: a preclinical study on goats
A1 - Zheng Gu
A1 - Xiangman Zhang
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J0 - Journal of Zhejiang University Science D
VL - 9
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SP - 1049
EP - 1058
%@ 1869-1951
Y1 - 2026
PB - Zhejiang University Press & Springer
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DOI - 10.1631/bdm.2600036


Abstract: 

一项搭载先进温控技术的双模射频消融导管治疗隐静脉及穿通静脉功能不全的临床前研究:基于山羊模型

为克服现有进口器械热损伤风险高、与国内临床常用的 6 Fr 鞘管不兼容等局限性,我们研发了一款名为 Saphenus 的新型国产射频消融(RFA)导管系统。其核心创新点包括:6 Fr 外径设计(适配国内常用鞘管),独特的双模工作长度设计(8 mm 用于穿通静脉,80 mm 用于大隐静脉),以及优化的温度传感机制以提供精准的热反馈。体外测试及山羊动物实验结果表明,Saphenus 系统可实现有效的血管闭合。术后超声及组织病理学分析证实,所有靶静脉均成功闭塞且未见再通,其疗效与对照组相当,但热损伤风险显著降低。综上,该系统为下肢静脉功能不全提供了一种安全、高效且经济的微创治疗方案,尤其契合中国临床实际需求。
关键词:射频消融;大隐静脉;穿通静脉;消融导管

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CLC number: 

On-line Access: 2026-08-13

Received: 2026-01-18

Revision Accepted: 2026-05-17

Crosschecked: 0000-00-00

Cited: 

Clicked: 48

Citations:  Bibtex RefMan EndNote GB/T7714

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