Bio-Design and Manufacturing  2026 Vol.9 No.4 P.617 - 725

http://doi.org/10.1631/bdm.2600246

Author(s):  Yunxia Chen,Kyle R. Phillips,Eben Alsberg,Thomas E. Angelini,Nasim Annabi,Anthony Atala,Amit Bandyopadhyay,Leon M. Bellan,Luiz E. Bertassoni,Adriana Blazeski,Thomas Boland,Susmita Bose,Jason A. Burdick,Robert C. Chang,Christopher S. Chen,Roland K. Chen,Douglas B. Chrisey,Elizabeth Cosgriff-Hernandez,Paul D. Dalton,David Dean,Aixiang Ding,Bin Duan,Marc Ferrer,John P. Fisher,Gabor Forgacs,Debolina Ghosh,Warren L. Grayson,Murat Guvendiren,MD Ahasan Habib,Sarah C. Heilshorn,Ashley Hicks,Scott J. Hollister,Congrui Jin,Yifei Jin,Roger D. Kamm,Bashir Khoda,Robert Langer,Cato T. Laurencin,Sang Jin Lee,Kam W. Leong,Ming C. Leu,Wei Li,Michael Mak,Amir K. Miri,Roger J. Narayan,Liqun Ning,Brenda M. Ogle,Ibrahim T. Ozbolat,Zhijian Pei,Peihua Qiu,Krishanu Saha,Jayant Saksena,Vahid Serpooshan,Albert Shih,Rohan A. Shirwaiker,Pranav Soman,Ali Tamayol,Mark W. Tibitt,Changxue Xu,Yunzhi Peter Yang,Lijie Grace Zhang,James J. Yoo,Shaochen Chen,Yu Shrike Zhang,Yong Huang

Affiliation(s):  1. Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, FL 32611, USA moreAffiliation(s): 1. Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, FL 32611, USA; 2. J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA; 3. Richard and Loan Hill Department of Biomedical Engineering, University of Illinois Chicago, Chicago, IL 60612, USA; 4. Jesse Brown Veterans Affairs Medical Center (JBVAMC), Chicago, IL 60612, USA; 5. Departments of Mechanical & Industrial Engineering, Orthopaedic Surgery, and Pharmacology and Regenerative Medicine, University of Illinois Chicago, Chicago, IL 60612, USA; 6. Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, FL 32611, USA; 7. J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA; 8. Department of Physics, University of Florida, Gainesville, FL 32611, USA; 9. Department of Materials Science and Engineering, University of Florida, Gainesville, FL 32611, USA; 10. Department of Chemical and Biomolecular Engineering, University of California Los Angeles, Los Angeles, CA 90095, USA; 11. Department of Bioengineering, University of California Los Angeles, Los Angeles, CA 90095, USA; 12. Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA; 13. School of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164, USA; 14. Department of Mechanical Engineering, Vanderbilt University, Nashville, TN 37235, USA; 15. Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235, USA; 16. Knight Cancer Precision Biofabrication Hub, Knight Cancer Institute (KCI), Oregon Health and Science University (OHSU), Portland, OR 97201, USA; 17. Cancer Early Detection Advanced Research Center (CEDAR), KCI, OHSU, Portland, OR 97201, USA; 18. Division of Oncological Sciences, School of Medicine, OHSU, Portland, OR 97201, USA; 19. Department of Biomedical Engineering, School of Medicine, OHSU, Portland, OR 97201, USA; 20. Department of Oral Rehabilitation Biosciences, School of Dentistry, OHSU, Portland, OR 97201, USA; 21. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; 22. Department of Metallurgical, Materials and Biomedical Engineering, University of Texas at El Paso, El Paso, TX 79965, USA; 23. School of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164, USA; 24. Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO 80303, USA; 25. BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303, USA; 26. Department of Mechanical Engineering, Stevens Institute of Technology, Hoboken, NJ 07030, USA; 27. Biological Design Center and Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA; 28. Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA; 29. School of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164, USA; 30. Department of Physics and Engineering Physics, Tulane University, New Orleans, LA 70118, USA; 31. Department of Biomedical Engineering, Tulane University, New Orleans, LA 70118, USA; 32. Department of Biomedical Engineering, University of Texas at Austin, Austin, TX 78712, USA; 33. Department of Bioengineering, Phil and Penny Knight Campus for Accelerating Scientific Impact, University of Oregon, Eugene, OR 97403, USA; 34. Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA; 35. Richard and Loan Hill Department of Biomedical Engineering, University of Illinois Chicago, Chicago, IL 60612, USA; 36. Mary & Dick Holland Regenerative Medicine Program, University of Nebraska Medical Center, Omaha, NE 68198, USA; 37. Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), The National Institutes of Health, Rockville, MD 20850, USA; 38. Fischell Department of Bioengineering, University of Maryland, College Park, MD 20742, USA; 39. Center for Engineering Complex Tissues, University of Maryland, College Park, MD 20742, USA; 40. Department of Physics, University of Missouri, Columbia, MO 65211, USA; 41. Fork & Good, Inc., Jersey City, NJ 07302, USA; 42. Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030, USA; 43. Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; 44. Translational Therapeutics & Regenerative Engineering Center, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA; 45. Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD 21218, USA; 46. Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD 21218, USA; 47. Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA; 48. Department of Chemical and Materials Engineering, New Jersey Institute of Technology, Newark, NJ 07102, USA; 49. Department of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ 07102, USA; 50. Department of Mechanical and Mechatronics Engineering Technology, Rochester Institute of Technology, Rochester, NY 14623, USA; 51. Department of Materials Science & Engineering, Stanford University, Stanford, CA 94305, USA; 52. Department of Biomedical Engineering, University of Texas at Austin, Austin, TX 78712, USA; 53. Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA; 54. Department of Engineering Technology and Industrial Distribution, Texas A&M University, College Station, TX 77843, USA; 55. Department of Mechanical Engineering, University of Nevada Reno, Reno, NV 89557, USA; 56. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; 57. Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; 58. Department of Mechanical Engineering, University of Maine, Orono, ME 04469, USA; 59. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; 60. David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; 61. Cato T. Laurencin Institute for Regenerative Engineering, University of Connecticut, Farmington, CT 06030, USA; 62. Department of Biomedical Engineering, University of Connecticut, Storrs, CT 06269, USA; 63. Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, CT 06030, USA; 64. Department of Materials Science and Engineering, University of Connecticut, Storrs, CT 06269, USA; 65. Department of Chemical and Biomolecular Engineering, University of Connecticut, Storrs, CT 06269, USA; 66. Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA; 67. Department of Biomedical Engineering, Columbia University, New York, NY 10025, USA; 68. Department of Systems Biology, Columbia University Medical Center, New York, NY 10032, USA; 69. Department of Mechanical and Aerospace Engineering, Missouri University of Science and Technology, Rolla, MO 65409, USA; 70. Walker Department of Mechanical Engineering, University of Texas at Austin, Austin, TX 78712, USA; 71. Department of Pharmacological Sciences, Stony Brook University, Stony Brook, NY, 11794, USA; 72. Department of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ 07102, USA; 73. Joint Department of Biomedical Engineering, University of North Carolina and North Carolina State University, Raleigh, NC 27695, USA; 74. Department of Materials Science and Engineering, North Carolina State University, Raleigh, NC 27695, USA; 75. Department of Mechanical Engineering, Cleveland State University, Cleveland, OH 44115, USA; 76. Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, USA; 77. Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA; 78. The Huck Institutes of Life Sciences, Penn State University, University Park, PA 16802, USA; 79. Engineering Science and Mechanics Department, Penn State University, University Park, PA 16802, USA; 80. Department of Biomedical Engineering, Penn State University, University Park, PA 16802, USA; 81. Materials Research Institute, Penn State University, University Park, PA 16802, USA; 82. Department of Neurosurgery, Penn State University, University Park, PA 16802, USA; 83. Cancer Institute, Penn State University, Hershey, PA 17033, USA; 84. Department of Industrial and Systems Engineering, Texas A&M University, College Station, TX 77843, USA; 85. Department of Biostatistics, University of Florida, Gainesville, FL 32610, USA; 86. Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA; 87. Wisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI 53715, USA; 88. Department of Physics and Engineering Physics, Tulane University, New Orleans, LA 70118, USA; 89. Department of Biomedical Engineering, Tulane University, New Orleans, LA 70118, USA; 90. Children’s Heart Institute, McGovern Medical School, UTHealth, Houston, TX 77030, USA; 91. Center for Innovation in Congenital Heart Disease, UTHealth, Houston, TX 77030, USA; 92. Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA; 93. Edward F. Pitts Department of Industrial & Systems Engineering, North Carolina State University, Raleigh, NC 27695, USA; 94. Bezos Center for Sustainable Protein, North Carolina State University, Raleigh, NC 27695, USA; 95. Comparative Medicine Institute, North Carolina State University, Raleigh, NC 27695, USA; 96. Department of Biomedical and Chemical Engineering, Syracuse University, Syracuse, NY 13244, USA; 97. Department of Biomedical Engineering, University of Connecticut Health Center, Farmington, CT 06030, USA; 98. Macromolecular Engineering Laboratory, Department of Mechanical and Process Engineering, ETH Zurich, Zurich 8092, Switzerland; 99. Department of Industrial, Manufacturing, and Systems Engineering, Texas Tech University, Lubbock, TX 79409, USA; 100. Department of Materials Science & Engineering, Stanford University, Stanford, CA 94305, USA; 101. Department of Orthopedic Surgery, Stanford University, Stanford, CA 94305, USA; 102. Department of Bioengineering, Stanford University, Stanford, CA 94305, USA; 103. Department of Mechanical and Aerospace Engineering, George Washington University, Washington, DC 20052, USA; 104. Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA; 105. Aiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California San Diego, La Jolla, CA 92093, USA; 106. Department of Bioengineering, University of California San Diego, La Jolla, CA 92093, USA; 107. Division of Engineering in Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Cambridge, MA 02139, USA; 108. Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA; 109. Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; 110. Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, FL 32611, USA; 111. J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA; 112. Department of Materials Science and Engineering, University of Florida, Gainesville, FL 32611, USA less

Corresponding email(s):   James.Yoo@wfusm.edu, shc064@ucsd.edu, yszhang@bwh.harvard.edu, yongh@ufl.edu

Key Words:  Biofabrication, Biomedical manufacturing, United States, Biomaterials, Physics modeling, Biomechanics