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Journal of Zhejiang University SCIENCE B 2019 Vol.20 No.6 P.503-512

http://doi.org/10.1631/jzus.B1900161


Pericarp and seed of litchi and longan fruits: constituent, extraction, bioactive activity, and potential utilization


Author(s):  Xiang-Rong Zhu, Hui Wang, Jian Sun, Bao Yang, Xue-Wu Duan, Yue-Ming Jiang

Affiliation(s):  Key Laboratory of Plant Resource Conservation and Sustainable Utilization, Key Laboratory of Post-Harvest Handling of Fruits, Ministry of Agriculture, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China; more

Corresponding email(s):   ymjiang@scbg.ac.cn

Key Words:  Bioactive compound, Extraction, Litchi, Longan, Pharmacological activity, Utilization


Xiang-Rong Zhu, Hui Wang, Jian Sun, Bao Yang, Xue-Wu Duan, Yue-Ming Jiang. Pericarp and seed of litchi and longan fruits: constituent, extraction, bioactive activity, and potential utilization[J]. Journal of Zhejiang University Science B, 2019, 20(6): 503-512.

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author="Xiang-Rong Zhu, Hui Wang, Jian Sun, Bao Yang, Xue-Wu Duan, Yue-Ming Jiang",
journal="Journal of Zhejiang University Science B",
volume="20",
number="6",
pages="503-512",
year="2019",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B1900161"
}

%0 Journal Article
%T Pericarp and seed of litchi and longan fruits: constituent, extraction, bioactive activity, and potential utilization
%A Xiang-Rong Zhu
%A Hui Wang
%A Jian Sun
%A Bao Yang
%A Xue-Wu Duan
%A Yue-Ming Jiang
%J Journal of Zhejiang University SCIENCE B
%V 20
%N 6
%P 503-512
%@ 1673-1581
%D 2019
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1900161

TY - JOUR
T1 - Pericarp and seed of litchi and longan fruits: constituent, extraction, bioactive activity, and potential utilization
A1 - Xiang-Rong Zhu
A1 - Hui Wang
A1 - Jian Sun
A1 - Bao Yang
A1 - Xue-Wu Duan
A1 - Yue-Ming Jiang
J0 - Journal of Zhejiang University Science B
VL - 20
IS - 6
SP - 503
EP - 512
%@ 1673-1581
Y1 - 2019
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1900161


Abstract: 
litchi (litchi chinensis Sonn.) and longan (Dimocarpus longan Lour.) fruits have a succulent and white aril with a brown seed and are becoming popular worldwide. The two fruits have been used in traditional Chinese medicine as popular herbs in the treatment of neural pain, swelling, and cardiovascular disease. The pericarp and seed portions as the by-products of litchi and longan fruits are estimated to be approximately 30% of the dry weight of the whole fruit and are rich in bioactive constituents. In the recent years, many biological activities, such as tyrosinase inhibitory, antioxidant, anti-inflammatory, immunomodulatory, anti-glycated, and anti-cancer activities, as well as memory-increasing effects, have been reported for the litchi and longan pericarp and seed extracts, indicating a potentially significant contribution to human health. With the increasing production of litchi and longan fruits, enhanced utilization of the two fruit by-products for their inherent bioactive constituents in relation to pharmacological effects is urgently needed. This paper reviews the current advances in the extraction, processing, identification, and biological and pharmacological activities of constituents from litchi and longan by-products. Potential utilization of litchi and longan pericarps and seeds in relation to further research is also discussed.

荔枝、龙眼的果皮和种子:成分、提取、生物活性和潜在利用

概要:荔枝(Litchi chinensis Sonn.)和龙眼(Dimocarpus longan Lour.)果肉白色透明,深受消费者欢迎.荔枝和龙眼果实作为我国传统中草药,可用于缓解神经疼痛和肿胀.荔枝和龙眼的果皮和种子部分占整个果实干重约30%,含有丰富的生物活性物质.近年来研究发现,荔枝和龙眼的果皮和种子的提取物具有抑制酪氨酸酶活性、抗炎、免疫调节、抗糖化、抗癌以及增强记忆等功能.随着荔枝和龙眼果实在世界上种植面积和数量的迅速增加,加强对生物活性物质的利用尤其必要.本文综述了对荔枝和龙眼的果皮和种子中生物活性化合物的鉴定、提取和药理活性等方面研究的最新进展,并讨论了其资源潜在利用以及未来研究方向.
关键词:活性物质;提取;荔枝;龙眼;药理活性;利用

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference

[1]Bai XL, Pan R, Li MZ, et al., 2019. HPLC profile of longan (cv. Shixia) pericarp-sourced phenolics and their antioxidant and cytotoxic effects. Molecules, 24(3):619.

[2]Bao T, Wang Y, Li YT, et al., 2016. Antioxidant and antidiabetic properties of tartary buckwheat rice flavonoids after in vitro digestion. J Zhejiang Univ-Sci B (Biomed & Biotechnol), 17(12):941-951.

[3]Baskaran XR, Geo Vigila AV, Zhang SZ, et al., 2018. A review of the use of pteridophytes for treating human ailments. J Zhejiang Univ-Sci B (Biomed & Biotechnol), 19(2):85-119.

[4]Chen JY, Ge ZZ, Zhu W, et al., 2014. Screening of key antioxidant compounds of longan (Dimocarpus longan Lour.) seed extract by combining online fishing/knockout, activity evaluation, Fourier transform ion cyclotron resonance mass spectrometry, and high-performance liquid chromatography electrospray ionization mass spectrometry methods. J Agric Food Chem, 62(40):9744-9750.

[5]Chen LG, Chang CW, Tsay JG, et al., 2017. Hepatoprotective effects of litchi (Litchi chinensis) procyanidin A2 on carbon tetrachloride-induced liver injury in ICR mice. Exp Ther Med, 13(6):2839-2847.

[6]Chen YY, Luo HY, Gao AP, et al., 2011. Ultrasound-assisted extraction of polysaccharides from litchi (Litchi chinensis Sonn.) seed by response surface methodology and their structural characteristics. Innov Food Sci Emerg Technol, 12(3):305-309.

[7]Choi SA, Lee JE, Kyung MJ, et al., 2017. Anti-diabetic functional food with wasted litchi seed and standard of quality control. Appl Biol Chem, 60(2):197-204.

[8]Emanuele S, Lauricella M, Calvaruso G, et al., 2017. Litchi chinensis as a functional food and a source of antitumor compounds: an overview and a description of biochemical pathways. Nutrients, 9(9):992.

[9]Gao WH, Lin PZ, Zeng XA, et al., 2017. Preparation, characterisation and antioxidant activities of litchi (Litchi chinensis Sonn.) polysaccharides extracted by ultra-high pressure. Int J Food Sci Technol, 52(8):1739-1750.

[10]Jiang GX, Prasad KN, Jiang YM, et al., 2009a. Extraction and structural identification of alkali-soluble polysaccharides of longan (Dimocarpus longan Lour.) fruit pericarp. Innov Food Sci Emerg Technol, 10(4):638-642.

[11]Jiang GX, Jiang YM, Yang B, et al., 2009b. Structural characteristics and antioxidant activities of oligosaccharides from longan fruit pericarp. J Agric Food Chem, 57(19):9293-9298.

[12]Jiang GX, Lin S, Wen LR, et al., 2013a. Identification of a novel phenolic compound in litchi (Litchi chinensis Sonn.) pericarp and bioactivity evaluation. Food Chem, 136(2):563-568.

[13]Jiang GX, Wen LR, Chen F, et al., 2013b. Structural characteristics and antioxidant activities of polysaccharides from longan seed. Carbohyd Polym, 92(1):758-764.

[14]Jiang YM, Zhang ZQ, Joyce DC, et al., 2002. Postharvest biology and handling of longan fruit (Dimocarpus longan Lour.). Postharvest Biol Technol, 26(3):241-252.

[15]Jiang YM, Wang Y, Song L, et al., 2006. Postharvest characteristics and handling of litchi fruit—an overview. Aust J Exp Agric, 46(12):1541-1556.

[16]Kanlayavattanakul M, Ospondpant D, Ruktanonchai U, et al., 2012. Biological activity assessment and phenolic compounds characterization from the fruit pericarp of Litchi chinensis for cosmetic applications. Pharm Biol, 50(11):1384-1390.

[17]Kessy HNE, Wang K, Zhao L, et al., 2018. Enrichment and biotransformation of phenolic compounds from litchi pericarps with angiotensin I-converting enzyme (ACE) inhibition activity. LWT, 87:301-309.

[18]Kunworarath N, Rangkadilok N, Suriyo T, et al., 2016. Longan (Dimocarpus longan Lour.) inhibits lipopolysaccharide-stimulated nitric oxide production in macrophages by suppressing NF-κB and AP-1 signaling pathways. J Ethnopharmacol, 179:156-161.

[19]Li JR, Jiang YM, 2007. Litchi flavonoids: isolation, identification and biological activity. Molecules, 12(4):745-758.

[20]Li XN, Huang JL, Wang ZD, et al., 2014. Alkaline extraction and acid precipitation of phenolic compounds from longan (Dimocarpus longan L.) seeds. Sep Purif Technol, 124:201-206.

[21]Lin S, Wen LR, Yang B, et al., 2013. Improved growth of Lactobacillus bulgaricus and Streptococcus thermophilus as well as increased antioxidant activity by biotransforming litchi pericarp polysaccharide with Aspergillus awamori. BioMed Res Int, 2013:413793.

[22]Lin S, He JR, Jiang YM, et al., 2014. Production of nigragillin and dihydrophaseic acid by biotransformation of litchi pericarp with Aspergillus awamori and their antioxidant activities. J Funct Foods, 7:278-286.

[23]Lin S, Li Q, Yang B, et al., 2016. Transformation of litchi pericarp-derived condensed tannin with Aspergillus awamori. Int J Mol Sci, 17(7):1067.

[24]Ma Q, Xie HH, Li S, et al., 2014a. Flavonoids from the pericarps of Litchi chinensis. J Agric Food Chem, 62(5):1073-1078.

[25]Ma Q, Xie HH, Jiang YM, et al., 2014b. Phenolics and sesquiterpenes from litchi pericarp. J Funct Foods, 9:156-161.

[26]Panyathep A, Chewonarin T, Taneyhill K, 2013. Antioxidant and anti-matrix metalloproteinases activities of dried longan (Euphoria longana) seed extract. Sci Asia, 39(4):12-18.

[27]Prasad KN, Hao J, Shi J, et al., 2009a. Antioxidant and anticancer activities of high pressure-assisted extract of longan (Dimocarpus longan Lour.) fruit pericarp. Innov Food Sci Emerg Technol, 10(4):413-419.

[28]Prasad KN, Yang B, Zhao MM, et al., 2009b. Application of ultrasonication or high-pressure extraction of flavonoids from litchi fruit pericarp. J Food Process Eng, 32(6):828-843.

[29]Prasad KN, Yang E, Yi C, et al., 2009c. Effects of high pressure extraction on the extraction yield, total phenolic content and antioxidant activity of longan fruit pericarp. Innov Food Sci Emerg Technol, 10(2):155-159.

[30]Prasad KN, Yang B, Zhao M, et al., 2010a. Effects of high pressure or ultrasonic treatment on extraction yield and antioxidant activity of pericarp tissues of longan fruit. J Food Biochem, 34(4):838-855.

[31]Prasad KN, Yang B, Shi J, et al., 2010b. Enhanced antioxidant and antityrosinase activities of longan fruit pericarp by ultra-high-pressure-assisted extraction. J Pharm Biomed Anal, 51(2):471-477.

[32]Rangkadilok N, Sitthimonchai S, Worasuttayangkurn L, et al., 2007. Evaluation of free radical scavenging and antityrosinase activities of standardized longan fruit extract. Food Chem Toxicol, 45(2):328-336.

[33]Rangkadilok N, Tongchusak S, Boonhok R, et al., 2012. In vitro antifungal activities of longan (Dimocarpus longan Lour.) seed extract. Fitoterapia, 83(3):545-553.

[34]Sarni-Manchado P, le Roux E, le Guerneve C, et al., 2000. Phenolic composition of litchi fruit pericarp. J Agric Food Chem, 48(12):5995-6002.

[35]Sudjaroen Y, Hull WE, Erben G, et al., 2012. Isolation and characterization of ellagitannins as the major polyphenolic components of longan (Dimocarpus longan Lour) seeds. Phytochemistry, 77:226-237.

[36]Sui Y, Zheng Y, Li XP, et al., 2016. Characterization and preparation of oligomeric procyanidins from Litchi chinensis pericarp. Fitoterapia, 112:168-174.

[37]Sun J, Shi J, Jiang YM, et al., 2007. Identification of two polyphenolic compounds with antioxidant activities in longan pericarp tissues. J Agric Food Chem, 55(14):5864-5868.

[38]Sun J, Li L, You XR, et al., 2011. Phenolics and polysaccharides in major tropical fruits: chemical compositions, analytical methods and bioactivities. Anal Methods, 3(10):2212-2220.

[39]Tseng HC, Wu WT, Huang HS, et al., 2014. Antimicrobial activities of various fractions of longan (Dimocarpus longan Lour. Fen Ke) seed extract. Int J Food Sci Nutr, 65(5):589-593.

[40]Wang HC, Hu ZQ, Wang Y, et al., 2011. Phenolic compounds and the antioxidant activities in litchi pericarp: difference among cultivars. Sci Hort, 129(4):784-789.

[41]Wang LJ, Lou GD, Ma ZJ, et al., 2011. Chemical constituents with antioxidant activities from litchi (Litchi chinensis Sonn.) seeds. Food Chem, 126(3):1081-1087.

[42]Wang XJ, Yuan SL, Wang J, 2006a. Anticancer activity of litchi fruit pericarp extract against human breast cancer in vitro and in vivo. Toxicol Appl Pharmacol, 215(2):168-178.

[43]Wang XJ, Wei YQ, Yuan SL, et al., 2006b. Potential anticancer activity of litchi fruit pericarp extract against hepatocellular carcinoma in vitro and in vivo. Cancer Lett, 239(1):144-150.

[44]Xu XY, Xie HH, Wang YF, et al., 2010. A-type proanthocyanidins from lychee seeds and their antioxidant and antiviral activities. J Agric Food Chem, 58(22):11667-11672.

[45]Yang B, Wang JS, Zhao MM, et al., 2006. Identification of polysaccharides from pericarp tissues of litchi (Litchi chinensis Sonn.) fruit in relation to their antioxidant activities. Carbohyd Res, 341(5):634-638.

[46]Yang B, Zhao MM, Shi J, et al., 2008a. Effect of ultrasonic treatment on the recovery and DPPH radical scavenging activity of polysaccharides from longan fruit pericarp. Food Chem, 106(2):685-690.

[47]Yang B, Zhao MM, Jiang YM, 2008b. Optimization of tyrosinase inhibition activity of ultrasonic-extracted polysaccharides from longan fruit pericarp. Food Chem, 110(2):294-300.

[48]Yang B, Zhao MM, Shi J, et al., 2008c. Variations in water-soluble saccharides and phenols in longan fruit pericarp after drying. J Food Process Eng, 31(1):66-77.

[49]Yang B, Zhao MM, Jiang YM, 2009a. Anti-glycated activity of polysaccharides of longan (Dimocarpus longan Lour.) fruit pericarp treated by ultrasonic wave. Food Chem, 114(2):629-633.

[50]Yang B, Jiang YM, Zhao MM, et al., 2009b. Structural characterisation of polysaccharides purified from longan (Dimocarpus longan Lour.) fruit pericarp. Food Chem, 115(2):609-614.

[51]Yang B, Jiang YM, Wang R, et al., 2009c. Ultra-high pressure treatment effects on polysaccharides and lignins of longan fruit pericarp. Food Chem, 112(2):428-431.

[52]Yang B, Jiang YM, Shi J, et al., 2011. Extraction and pharmacological properties of bioactive compounds from longan (Dimocarpus longan Lour.) fruit—a review. Food Res Int, 44(7):1837-1842.

[53]Zhang JC, Yang GM, Wen YZ, et al., 2017. Intestinal microbiota are involved in the immunomodulatory activities of longan polysaccharide. Mol Nutr Food Res, 61(11):1700466.

[54]Zhang RF, Su DX, Hou FL, et al., 2017. Optimized ultra-high-pressure-assisted extraction of procyanidins from lychee pericarp improves the antioxidant activity of extracts. Biosci Biotechnol Biochem, 81(8):1576-1585.

[55]Zhao MM, Yang B, Wang JS, et al., 2006. Identification of the major flavonoids from pericarp tissues of lychee fruit in relation to their antioxidant activities. Food Chem, 98(3):539-544.

[56]Zhao MM, Yang B, Wang JS, et al., 2007. Immunomodulatory and anticancer activities of flavonoids extracted from litchi (Litchi chinensis Sonn.) pericarp. Int Immunopharmacol, 7(2):162-166.

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