Full Text:
<20>
CLC number:
On-line Access: 2024-12-30
Received: 2024-05-20
Revision Accepted: 2024-10-07
Crosschecked: 0000-00-00
Cited: 0
Clicked: 36
Role of Wnt ligands and receptors in oral squamous cell carcinoma
| |||||||||||||
Muhammad TUFAIL, Cai-Yun HE, Can-Hua JIANG, Ning LI. Role of Wnt ligands and receptors in oral squamous cell carcinoma[J]. Journal of Zhejiang University Science B, 1998, -1(-1): .
@article{title="Role of Wnt ligands and receptors in oral squamous cell carcinoma",
author="Muhammad TUFAIL, Cai-Yun HE, Can-Hua JIANG, Ning LI",
journal="Journal of Zhejiang University Science B",
volume="-1",
number="-1",
pages="",
year="1998",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B2400251"
}
%0 Journal Article
%T Role of Wnt ligands and receptors in oral squamous cell carcinoma
%A Muhammad TUFAIL
%A Cai-Yun HE
%A Can-Hua JIANG
%A Ning LI
%J Journal of Zhejiang University SCIENCE B
%V -1
%N -1
%P
%@ 1673-1581
%D 1998
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2400251
TY - JOUR
T1 - Role of Wnt ligands and receptors in oral squamous cell carcinoma
A1 - Muhammad TUFAIL
A1 - Cai-Yun HE
A1 - Can-Hua JIANG
A1 - Ning LI
J0 - Journal of Zhejiang University Science B
VL - -1
IS - -1
SP -
EP -
%@ 1673-1581
Y1 - 1998
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B2400251
Abstract: oral squamous cell carcinoma (OSCC) poses significant challenges in terms of diagnosis and treatment, with high rates of morbidity and mortality. Emerging evidence highlights the critical involvement of Wnt ligands and receptors in OSCC patho-genesis. Dysregulated wnt signaling pathways' contribution to tumor initiation, progression, and therapy resistance is character-ized by their ability to promote cellular proliferation, epithelial-mesenchymal transition (EMT), and the maintenance of cancer stem cells (CSCs). Targeting wnt signaling presents a promising therapeutic avenue, yet its complex interplay with other signaling pathways requires a deeper understanding to implement effective intervention. This study sheds light on the current knowledge of the role of Wnt ligands and receptors in OSCC, emphasizing their potential as diagnostic biomarkers and therapeutic targets. Future research directions involve elucidating context-specific wnt signaling dynamics and exploring combination therapies to improve clinical outcomes for OSCC patients.
Open peer comments: Debate/Discuss/Question/Opinion
<1>