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Journal of Zhejiang University SCIENCE B 2006 Vol.7 No.5 P.342-350


Interactions between mycoplasma lipid-associated membrane proteins and the host cells

Author(s):  You Xiao-xing, Zeng Yan-hua, Wu Yi-mou

Affiliation(s):  Institute of Pathogenic Biology, School of Medicine, Nanhua University, Hengyang 421001, China

Corresponding email(s):   yimouwu@sina.com

Key Words:  Mycoplasma, Lipid-associated membrane proteins (LAMPs), Toll-like receptor (TLR), Immunomodulin

You Xiao-xing, Zeng Yan-hua, Wu Yi-mou. Interactions between mycoplasma lipid-associated membrane proteins and the host cells[J]. Journal of Zhejiang University Science B, 2006, 7(5): 342-350.

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author="You Xiao-xing, Zeng Yan-hua, Wu Yi-mou",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

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%T Interactions between mycoplasma lipid-associated membrane proteins and the host cells
%A You Xiao-xing
%A Zeng Yan-hua
%A Wu Yi-mou
%J Journal of Zhejiang University SCIENCE B
%V 7
%N 5
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%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2006.B0342

T1 - Interactions between mycoplasma lipid-associated membrane proteins and the host cells
A1 - You Xiao-xing
A1 - Zeng Yan-hua
A1 - Wu Yi-mou
J0 - Journal of Zhejiang University Science B
VL - 7
IS - 5
SP - 342
EP - 350
%@ 1673-1581
Y1 - 2006
PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.2006.B0342

Mycoplamas are a group of wall-less prokaryotes widely distributed in nature, some of which are pathogenic for humans and animals. There are many lipoproteins anchored on the outer face of the plasma membrane, called lipid-associated membrane proteins (LAMPs). LAMPs are highly antigenic and could undergo phase and size variation, and are recognized by the innate immune system through Toll-like receptors (TLR) 2 and 6. LAMPs can modulate the immune system, and could induce immune cells apoptosis or death. In addition, they may associate with malignant transformation of host cells and are also considered to be cofactors in the progression of AIDS.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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