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Received: 2007-07-16

Revision Accepted: 2007-08-06

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Journal of Zhejiang University SCIENCE B 2007 Vol.8 No.10 P.721-724


Pulmonary actinomycosis: a case undergoing resection through video-assisted thoracic surgery (VATS)

Author(s):  LIN Ming-shian, LIN Wea-lung, LUH Shi-ping, TSAO Thomas Chang-yao, WU Tzu-ching

Affiliation(s):  Department of Medicine, Chia-Yi Christian Hospital, 600 Taichung, Taiwan, China; more

Corresponding email(s):   luh572001@yahoo.com.tw

Key Words:  Pulmonary actinomycosis, Video-assisted thoracic surgery (VATS), Resection

LIN Ming-shian, LIN Wea-lung, LUH Shi-ping, TSAO Thomas Chang-yao, WU Tzu-ching. Pulmonary actinomycosis: a case undergoing resection through video-assisted thoracic surgery (VATS)[J]. Journal of Zhejiang University Science B, 2007, 8(10): 721-724.

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author="LIN Ming-shian, LIN Wea-lung, LUH Shi-ping, TSAO Thomas Chang-yao, WU Tzu-ching",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Pulmonary actinomycosis: a case undergoing resection through video-assisted thoracic surgery (VATS)
%A LIN Ming-shian
%A LIN Wea-lung
%A LUH Shi-ping
%A TSAO Thomas Chang-yao
%A WU Tzu-ching
%J Journal of Zhejiang University SCIENCE B
%V 8
%N 10
%P 721-724
%@ 1673-1581
%D 2007
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2007.B0721

T1 - Pulmonary actinomycosis: a case undergoing resection through video-assisted thoracic surgery (VATS)
A1 - LIN Ming-shian
A1 - LIN Wea-lung
A1 - LUH Shi-ping
A1 - TSAO Thomas Chang-yao
A1 - WU Tzu-ching
J0 - Journal of Zhejiang University Science B
VL - 8
IS - 10
SP - 721
EP - 724
%@ 1673-1581
Y1 - 2007
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2007.B0721

Actinomycosis is an uncommon disease, which is usually manifested as cervicofacial infection and related to poor oral hygiene or compromised immune function. pulmonary actinomycosis is rare, but its diagnosis is changing due to its variable presentation and the similarity in appearance to other intrapulmonary diseases. Here we report an 80-year-old man with a solitary pulmonary nodule over the left upper lobe. Pulmonary neoplasm was highly suspected in this patient and thus resection of the mass was undertaken through video-assisted thoracic surgery (VATS). Histopathological examination demonstrated this patient had an Actinomyeces infection. While the application of VATS in patients with pulmonary actinomycosis has rarely been reported in literature, we conclude that VATS is valuable for the diagnosis and treatment of patients with undetermined pulmonary nodule(s).

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


[1] Allen, H.A.III, Scatarige, J.C., Kim, M.H., 1987. Actinomycosis: CT findings in six patients. AJR, 149(6):1255-1258.

[2] Ariel, I., Breuer, R., Kamal, N.S., Ben-Dov, I., Mogle, P., Rosenmann, E., 1991. Endobronchial actinomycosis simulating bronchogenic carcinoma: diagnosis by biopsy. Chest, 99(2):493-495.

[3] Bennhoff, D.F., 1984. Actinomycosis: diagnostic and therapeutic considerations and review of 32 cases. Laryngoscope, 94(9):1198-1217.

[4] Brown, J.R., 1973. Human actinomycosis. A study of 181 subjects. Human Pathol., 4(3):319-330.

[5] Conant, E.F., Wechsler, R.J., 1992. Actinomycosis and nocardiosis of the lung. J. Thorac. Imaging, 7(4):75-84.

[6] Das, D.K., 1994. Actinomycosis in fine needle aspiration cytology. Cytopathology, 5(4):243-250.

[7] Flynn, M.W., Felson, B., 1970. The roentgen manifestations of thoracic actinomycosis. AJR, 110(4):707-716.

[8] Heffner, J.E., 1988. Pleuropulmonary manifestations of actinomycosis and nocardiosis. Semin. Respir. Infect., 3(4):352-361.

[9] Hoekstra, C.J., Hoekstra, O.S., Teengs, J.P., Postmus, P.E., Smit, E.F., 1999. Thoracic actinomycosis imaging with fluorine-18 fluorodeoxyglucose positron emission tomography. Clin. Nucl. Med., 24(7):529-530.

[10] Holm, P., 1950. Studies on the aetiology of human actinomycosis. I. The “other” microbes of actinomycosis and their importance. Acta Pathol. Microbiol. Scand., 27(3):736.

[11] Kakuda, J., Omari, B., Renslo, R., Scott, R., Baumgartner, F., 1997. CT guided needle localization for video-thoraco-scopic resection of pulmonary nodules. Eur. J. Med. Res., 2(8):340-342.

[12] Kinnear, W.J., MacFarlane, J.T., 1990. A survey of thoracic actinomycosis. Respir. Med., 84(1):57-59.

[13] Klapholz, A., Talavera, W., Rorat, E., Salsitz, E., Widrow, C., 1989. Pulmonary actinomycosis and human immunodeficiency virus infection. Mt. Sinai. J. Med., 56(4):300-303.

[14] Kobashi, Y., Yoshida, K., Miyashita, N., Niki, Y., Matsushima, T., 2004. Thoracic actinomycosis with mainly pleural involvement. J. Infect. Chemother., 10(3):172-177.

[15] Lippes, J., 1999. Pelvic actinomycosis: a review and preliminary look at prevalence. Am. J. Obstet. Gynaecol., 180(2):265-269.

[16] Luh, S.P., Liu, H.P., 2006. Video-assisted thoracic surgery. The past, present status, and the future. J. Zhejiang Univ. Sci. B, 7(2):118-128.

[17] Mabeza, G.F., MacFarlane, J., 2003. Pulmonary actinomycosis. Eur. Respir. J., 21(3):545-551.

[18] Miller, M., Haddad, A.J., 1998. Cervicofacial actinomycosis. Oral Surg. Oral Med. Oral Path. Oral Radiol. Endod., 85(5):496-508.

[19] Moore, W.R., Scannell, J.G., 1968. Pulmonary actinomycosis simulating cancer of the lung. J. Thorac. Cardiovasc. Surg., 55(2):193-195.

[20] Reichel, R., Wragg, P., 2007. Isolation of actinomyces hyovaginalis from a lung lesion in a pig. Vet. Rec., 10(6):203.

[21] Rippon, J.W., 1988. Medical Mycology. In: Wonsiewicz, M.J. (Ed.), The Pathogenic Fungi and the Pathogenic Actinomycetes, 3rd Ed. W.B. Saunders Co., Philadelphia, p.30-52.

[22] Russo, T.A., 1995. Agents of Actinomycosis. In: Mandell, G.L. (Ed.), Principles and Practice of Infectious Disease, 5th Ed. Churchill Livingstone, New York, p.2645-2654.

[23] Schaal, K.P., Lee, H., 1992. Actinomycete infections in human—a review. Gene, 115(1-2):201-211.

[24] Slade, P.R., Slesser, B.V., Southgate, J., 1973. Thoracic actinomycosis. Thorax, 28(1):73-85.

[25] Smego, R.A., Foglia, G., 1998. Actinomycosis. Clin. Infect. Dis., 26(6):1255-1261 (quiz in p.1262-1263).

[26] Weese, W.C., Smith, I.M., 1975. A study of 57 cases of actinomycosis over a 36-year period. Arch. Intern. Med., 135(12):1562-1568.

[27] Wong, R.H., Sihoe, A.D., Thung, K.H., Wan, I.Y., Ip, M.B., Yim, A.P., 2004. Actinomycosis: an often forgotten diagnosis. Asian Cardiovasc. Thorac. Ann., 12(2):165-167.

[28] Yew, W.W., Wong, P.C., Lee, J., Fung, S.L., Wong, C.F., Chan, C.Y., 1999. Report of eight cases of pulmonary actinomycosis and their treatment with imipenem-cilastatin. Monaldi. Arch. Chest. Dis., 54(2):126-129.

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