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CLC number: R58

On-line Access: 2010-03-10

Received: 2009-11-20

Revision Accepted: 2010-01-11

Crosschecked: 2010-02-03

Cited: 3

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Citations:  Bibtex RefMan EndNote GB/T7714

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Journal of Zhejiang University SCIENCE B 2010 Vol.11 No.3 P.218-220

http://doi.org/10.1631/jzus.B0900371


Recurrent severe vomiting due to hyperthyroidism


Author(s):  Li-ying Chen, Bo Zhou, Zhou-wen Chen, Li-zheng Fang

Affiliation(s):  Department of Family Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China, Department of Family Medicine, Community Health Services Center in Pengbu Town, Hangzhou 310017, China

Corresponding email(s):   hsh0906@163.com

Key Words:  Vomiting, Hyperthyroidism, Peptic ulcer


Li-ying Chen, Bo Zhou, Zhou-wen Chen, Li-zheng Fang. Recurrent severe vomiting due to hyperthyroidism[J]. Journal of Zhejiang University Science B, 2010, 11(3): 218-220.

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T1 - Recurrent severe vomiting due to hyperthyroidism
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A1 - Li-zheng Fang
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VL - 11
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PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.B0900371


Abstract: 
Thyrotoxicosis may present in many ways; severe vomiting as a prominent symptom of thyrotoxicosis is uncommon. In this paper, we report a 24-year-old Chinese male with hyperthyroidism who presented with recurrent severe vomiting. The patient had had intermittent vomiting for seven years and had lost approximately 15 kg of weight. Gastroscopic examinations revealed chronic gastritis and one occasion peptic ulcer. He was treated with antacid and proton pump inhibitors, but his symptoms had no relief. His presenting symptoms suggested hyperthyroidism and were confirmed by laboratory data. After a month of propylthiouracil therapy, his symptoms were relieved. It should be noted that hyperthyroidism patients can have unexplained vomiting, and that hyperthyroidism may coexist with peptic ulcer in rare cases. Awareness of such atypical presentations of hyperthyroidism may help to make a correct diagnosis.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference

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[3]Bilezikian, J.P., Loeb, J.N., 1983. The influence of hyperthyroidism and hypothyroidism on alpha- and beta-adrenergic receptor systems and adrenergic responsiveness. Endocr. Rev., 4(4):378-388.

[4]Chen, P., Chen, H.F., Tan, S.W., Su, M.C., Ng, K.W., Jiang, C.F., 2003. Severely sustained vomiting as the main symptom in a man with thyrotoxicosis. J. Chin. Med. Assoc., 66(5):311-314.

[5]Crile, G., 1934. Hyperthyroidism and associated disease. Surg. Gynec. Obstet., 58:272-276.

[6]Garbat, A.L., 1951. The simultaneous occurrence of active peptic ulcer and active hyperthyroidism. J. Mount Sinai Hosp. NY, 17:787-792.

[7]Kisakol, G., Kayacetin, E., Sari, O., Kaya, A., 2003. Gastric emptying in subclinical hyperthyroidism. Neuro. Endocrinol. Lett., 24(3-4):255-258.

[8]Rosenthal, F.D., Jones, C., Lewis, S.I., 1976. Thyrotoxic vomiting. BMJ, 2(6029):209-211.

[9]Sellin, J.H., Vassiopoulou-Sellin, R., 2000. The Gastrointestinal Tract and Liver in Thyrotoxicosis. In: Braverman, L. (Ed.), Werner and Ingbar’s the Thyroid. Lippincott Williams and Wikin, Philadelphia, p.622-626.

[10]Xu, Z.S., Hu, X.J., Yang, G.J., Yan, C.G., Bao, Z.Y., 2007. Diagnosis analysis of 132 cases with vomiting as the main presentation due to hyperthyroidism. Chin. J. Pract. Intern. Med., 27(15):1215-1216.

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