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Xiang-hua Yan

http://orcid.org/0000-0003-2238-6218

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Journal of Zhejiang University SCIENCE B 2015 Vol.16 No.6 P.413-416

http://doi.org/10.1631/jzus.B1500130


Molecular nutrition: basic understanding of the digestion, absorption, and metabolism of nutrients


Author(s):  Xiang-hua Yan

Affiliation(s):  College of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan 430070, China

Corresponding email(s):   xhyan@mail.hzau.edu.cn

Key Words:  Molecular nutrition, Omics, Metabolism


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Xiang-hua Yan. Molecular nutrition: basic understanding of the digestion, absorption, and metabolism of nutrients[J]. Journal of Zhejiang University Science B, 2015, 16(6): 413-416.

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Abstract: 
molecular nutrition has emerged as a new area in nutritional science following both advances in mo-lecular biology and requirements for explaining the organism’s responses to nutrients at a molecular level. These include gene expression, signal transduction, and covalent modifications of proteins (Müller and Kersten, 2003). Jacob and Monod (1961) first de-veloped the lactose operon theory, which is the first example of gene regulation by a nutrient. Shapiro et al. (1969) isolated pure lactose operon DNA from Escherichia coli, thereby fully demonstrating the lactose operon model of Jacob and Monod (1961). Gene-nutrient interactions are the paradigm for the interplay between the genome and the environment. Every nutritional process relies on the interplay of a large number of proteins encoded by mRNA mole-cules that are expressed in a given cell. Alterations of mRNA levels and in turn of the corresponding protein levels (although the two variables do not necessarily change in parallel) are critical parameters in control-ling the flux of a nutrient or metabolite through a biochemical pathway. Thus, molecular nutrition helped address fundamental questions of health and provided exquisite mechanistic explanations of the cause and effect.

分子营养学:解析营养物质在体内的消化、吸收和代谢过程的分子机理

概要:分子营养学是营养科学近年来发展的一个重要研究方向,主要研究营养物质在动物机体内消化、吸收、代谢与利用等过程中的分子机理。随着组学技术渗透到营养科学研究领域,分子营养学得到迅猛的发展。营养物质在消化、吸收和代谢过程中的分子机理解析有助于进一步揭开动物营养学研究领域的"黑箱"理论,为动物健康养殖提供科学依据。
关键词:分子营养学;组学技术;吸收;代谢

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

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