CLC number: R575.3
On-line Access: 2024-08-27
Received: 2023-10-17
Revision Accepted: 2024-05-08
Crosschecked: 2020-08-17
Cited: 0
Clicked: 4152
Citations: Bibtex RefMan EndNote GB/T7714
Jing-wen Deng, Qin Yang, Xiao-peng Cai, Jia-ming Zhou, Wei-gao E, Yan-dong An, Qiu-xian Zheng, Meng Hong, Yan-li Ren, Jun Guan, Gang Wang, Shu-jing Lai, Zhi Chen. Early use of dexamethasone increases Nr4a1 in Kupffer cells ameliorating acute liver failure in mice in a glucocorticoid receptor-dependent manner[J]. Journal of Zhejiang University Science B, 2020, 21(9): 727-739.
@article{title="Early use of dexamethasone increases Nr4a1 in Kupffer cells ameliorating acute liver failure in mice in a glucocorticoid receptor-dependent manner",
author="Jing-wen Deng, Qin Yang, Xiao-peng Cai, Jia-ming Zhou, Wei-gao E, Yan-dong An, Qiu-xian Zheng, Meng Hong, Yan-li Ren, Jun Guan, Gang Wang, Shu-jing Lai, Zhi Chen",
journal="Journal of Zhejiang University Science B",
volume="21",
number="9",
pages="727-739",
year="2020",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B2000249"
}
%0 Journal Article
%T Early use of dexamethasone increases Nr4a1 in Kupffer cells ameliorating acute liver failure in mice in a glucocorticoid receptor-dependent manner
%A Jing-wen Deng
%A Qin Yang
%A Xiao-peng Cai
%A Jia-ming Zhou
%A Wei-gao E
%A Yan-dong An
%A Qiu-xian Zheng
%A Meng Hong
%A Yan-li Ren
%A Jun Guan
%A Gang Wang
%A Shu-jing Lai
%A Zhi Chen
%J Journal of Zhejiang University SCIENCE B
%V 21
%N 9
%P 727-739
%@ 1673-1581
%D 2020
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2000249
TY - JOUR
T1 - Early use of dexamethasone increases Nr4a1 in Kupffer cells ameliorating acute liver failure in mice in a glucocorticoid receptor-dependent manner
A1 - Jing-wen Deng
A1 - Qin Yang
A1 - Xiao-peng Cai
A1 - Jia-ming Zhou
A1 - Wei-gao E
A1 - Yan-dong An
A1 - Qiu-xian Zheng
A1 - Meng Hong
A1 - Yan-li Ren
A1 - Jun Guan
A1 - Gang Wang
A1 - Shu-jing Lai
A1 - Zhi Chen
J0 - Journal of Zhejiang University Science B
VL - 21
IS - 9
SP - 727
EP - 739
%@ 1673-1581
Y1 - 2020
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B2000249
Abstract: Background and objective: acute liver failure (ALF) is a type of disease with high mortality and rapid progression with no specific treatment methods currently available. glucocorticoids exert beneficial clinical effects on therapy for ALF. However, the mechanism of this effect remains unclear and when to use glucocorticoids in patients with ALF is difficult to determine. The purpose of this study was to investigate the specific immunological mechanism of dexamethasone (Dex) on treatment of ALF induced by lipopolysaccharide (LPS)/
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