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In vivo antioxidant activity of rabbiteye blueberry (Vaccinium ashei cv. ‘Brightwell’) anthocyanin extracts
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Jing Wang, Xingyu Zhao, Jiawei Zheng, Daniela D. Herrera-Balandrano, Xiaoxiao Zhang, Wuyang Huang, Zhongquan Sui. In vivo antioxidant activity of rabbiteye blueberry (Vaccinium ashei cv. ‘Brightwell’) anthocyanin extracts[J]. Journal of Zhejiang University Science B, 1998, -1(-1): .
@article{title="In vivo antioxidant activity of rabbiteye blueberry (Vaccinium ashei cv. ‘Brightwell’) anthocyanin extracts",
author="Jing Wang, Xingyu Zhao, Jiawei Zheng, Daniela D. Herrera-Balandrano, Xiaoxiao Zhang, Wuyang Huang, Zhongquan Sui",
journal="Journal of Zhejiang University Science B",
volume="-1",
number="-1",
pages="",
year="1998",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B2200590"
}
%0 Journal Article
%T In vivo antioxidant activity of rabbiteye blueberry (Vaccinium ashei cv. ‘Brightwell’) anthocyanin extracts
%A Jing Wang
%A Xingyu Zhao
%A Jiawei Zheng
%A Daniela D. Herrera-Balandrano
%A Xiaoxiao Zhang
%A Wuyang Huang
%A Zhongquan Sui
%J Journal of Zhejiang University SCIENCE B
%V -1
%N -1
%P
%@ 1673-1581
%D 1998
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2200590
TY - JOUR
T1 - In vivo antioxidant activity of rabbiteye blueberry (Vaccinium ashei cv. ‘Brightwell’) anthocyanin extracts
A1 - Jing Wang
A1 - Xingyu Zhao
A1 - Jiawei Zheng
A1 - Daniela D. Herrera-Balandrano
A1 - Xiaoxiao Zhang
A1 - Wuyang Huang
A1 - Zhongquan Sui
J0 - Journal of Zhejiang University Science B
VL - -1
IS - -1
SP -
EP -
%@ 1673-1581
Y1 - 1998
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B2200590
Abstract: Blueberries are rich in phenolic compounds including anthocyanins which are closely related to biological health functions. The purpose of this study was to investigate the antioxidant activity of blueberry anthocyanins extracted from ‘Brightwell’ rabbiteye blueberries in mice. After one week of adaptation, C57BL/6J healthy male mice were divided into different groups that were administered with 100, 400, or 800 mg/kg BAE (blueberry anthocyanin extract), and sacrificed at different time points (0.1, 0.5, 1, 2, 4, 8, or 12 h). The plasma, eyeballs, intestines, liver, and adipose tissues were collected to compare their antioxidant activities, including total antioxidant capacity (T-AOC), the antioxidant enzymes superoxide dismutase (SOD) and glutathione-peroxidase (GSH-PX or GPX), and the oxidative stress marker malondialdehyde (MDA). The results showed that blueberry anthocyanins had positive concentration-dependent antioxidant activity in vivo. The greater the blueberry anthocyanin concentration, the higher the T-AOC values, but the lower the MDA levels. The enzyme activity of SOD, the content of GSH-PX, and mRNA levels of Cu,Zn-SOD, Mn-SOD, and GPX all confirmed BAE played an antioxidant role after digestion in mice by improving their antioxidant defense. The In vivo antioxidant activity of BAE indicated that blueberry anthocyanins could be developed into functional foods or nutraceuticals with the aim of preventing or treating oxidative stress-related diseases.
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