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Journal of Zhejiang University SCIENCE B 2023 Vol.24 No.10 P.905-921


Application of interim PET-CT in first-line treatment decision-making for lymphoma

Author(s):  Linlin HUANG, Yi ZHAO, Jingsong HE

Affiliation(s):  Bone Marrow Transplantation Center, Department of Hematology, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China

Corresponding email(s):   hejingsong@zju.edu.cn, zhaoyi999@zju.edu.cn

Key Words:  Positron emission tomography-computed tomography (PET-CT), Lymphoma, Interim PET (iPET)‍, -adapted therapy

Linlin HUANG, Yi ZHAO, Jingsong HE. Application of interim PET-CT in first-line treatment decision-making for lymphoma[J]. Journal of Zhejiang University Science B, 2023, 24(10): 905-921.

@article{title="Application of interim PET-CT in first-line treatment decision-making for lymphoma",
author="Linlin HUANG, Yi ZHAO, Jingsong HE",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Application of interim PET-CT in first-line treatment decision-making for lymphoma
%A Linlin HUANG
%A Jingsong HE
%J Journal of Zhejiang University SCIENCE B
%V 24
%N 10
%P 905-921
%@ 1673-1581
%D 2023
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2200644

T1 - Application of interim PET-CT in first-line treatment decision-making for lymphoma
A1 - Linlin HUANG
A1 - Yi ZHAO
A1 - Jingsong HE
J0 - Journal of Zhejiang University Science B
VL - 24
IS - 10
SP - 905
EP - 921
%@ 1673-1581
Y1 - 2023
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B2200644

Recent advances in lymphoma treatment have significantly improved the survival of patients; however, the current approaches also have varying side effects. To overcome these, it is critical to implement individualized treatment according to the patient’s condition. Therefore, the early identification of high-risk groups and targeted treatment are important strategies for prolonging the survival time and improving the quality of life of patients. Interim positron emission tomography-computed tomography (PET-CT) has a high prognostic value, which can reflect chemosensitivity and identify patients for whom treatment may fail under this regimen. To date, many prospective clinical studies on interim PET (iPET)‍;-adapted therapy have been conducted. In this review, we focus on the treatment strategies entailed in these studies, as well as the means and timing of iPET assessment, with the aim of exploring the efficacy and existing issues regarding iPET-adapted treatment. It is expected that the improved use of PET-CT examination can facilitate treatment decision-making to identify precise treatment options.




Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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