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On-line Access: 2025-04-23
Received: 2024-06-18
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Functional redundancy of three mitochondrial Mg2+/Mn2+-dependent protein phosphatases (PPMs) in Toxoplasma gondii
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Kaiyin SHENG, Xueqiu CHEN, Yimin YANG, Jie XIA, Kaiyue SONG, Chaoqun YAO, Yi YANG, Aifang DU, Guangxu MA. Functional redundancy of three mitochondrial Mg2+/Mn2+-dependent protein phosphatases (PPMs) in Toxoplasma gondii[J]. Journal of Zhejiang University Science B, 2025, 26(4): 405-408.
@article{title="Functional redundancy of three mitochondrial Mg2+/Mn2+-dependent protein phosphatases (PPMs) in Toxoplasma gondii",
author="Kaiyin SHENG, Xueqiu CHEN, Yimin YANG, Jie XIA, Kaiyue SONG, Chaoqun YAO, Yi YANG, Aifang DU, Guangxu MA",
journal="Journal of Zhejiang University Science B",
volume="26",
number="4",
pages="405-408",
year="2025",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B2400308"
}
%0 Journal Article
%T Functional redundancy of three mitochondrial Mg2+/Mn2+-dependent protein phosphatases (PPMs) in Toxoplasma gondii
%A Kaiyin SHENG
%A Xueqiu CHEN
%A Yimin YANG
%A Jie XIA
%A Kaiyue SONG
%A Chaoqun YAO
%A Yi YANG
%A Aifang DU
%A Guangxu MA
%J Journal of Zhejiang University SCIENCE B
%V 26
%N 4
%P 405-408
%@ 1673-1581
%D 2025
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2400308
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T1 - Functional redundancy of three mitochondrial Mg2+/Mn2+-dependent protein phosphatases (PPMs) in Toxoplasma gondii
A1 - Kaiyin SHENG
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A1 - Jie XIA
A1 - Kaiyue SONG
A1 - Chaoqun YAO
A1 - Yi YANG
A1 - Aifang DU
A1 - Guangxu MA
J0 - Journal of Zhejiang University Science B
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PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.B2400308
Abstract: Toxoplasma gondii is a single-celled parasite that infects nearly all warm-blooded animals, including humans (Montoya and Liesenfeld, 2004). It occurs worldwide and can persist for a lifetime in mammals. Humans get infected by eating undercooked meat of animals containing the tissue cysts of this parasite. In immune-competent individuals, T. gondii infection usually does not cause significant clinical symptoms, whereas in pregnant or immunocompromised individuals, T. gondii infection (toxoplasmosis) can cause more serious problems like abortion and even death (Dunn et al., 1999; Wang et al., 2017). A combination of pyrimethamine and sulfadiazine is usually used to treat toxoplasmosis, although it is generally inefficient and causes side effects (Alday and Doggett, 2017). Worse still, there is a lack of vaccines to prevent T. gondii infection in humans or animals.
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