Current Issue: <JZUS-B>

 

Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)

ISSNs 1673-1581 (Print); 1862-1783 (Online); CN 33-1356/Q; started in 2005,Monthly.


JZUS-B is an international "Biomedicine & Biotechnology" reviewed-Journal indexed by SCI-E, MEDLINE, PMC, BA, BIOSIS Previews, JST, ZR, CA, SA, AJ, ZM, CABI, CSA, etc., and supported by the National Natural Science Foundation of China. It mainly covers research in Biomedicine, Biochemistry and Biotechnology, etc.

Impact factor: 1.099 (2011), 1.108 (2012), 1.293 (2013), 1.278 (2014), 1.303 (2015), 1.676 (2016), 1.815 (2017), 1.879 (2018).


Journal of Zhejiang University SCIENCE B

ISSN 1673-1581(Print), 1862-1783(Online), Monthly

CONTENTS

Treatment of large bone defects in load-bearing bone: traditional and novel bone grafts

Dan YU, Wenyi SHEN, Jiahui DAI, Huiyong ZHU

DOI: 10.1631/jzus.B2300669 Downloaded: 1218 Clicked: 1239 Cited: 0 Commented: 0(p.) <Full Text>

Genetic structure and admixture of Yi and Qiang in Southwestern China

Jun LIU1,2, Li JIANG2, Yongqiang KONG3, Chunnian WANG4, Shuo FENG2, Xuanzhu CHEN3, Deqin ZHANG5, Chuan-Chao WANG6,7,8, Caixia LI2

DOI: 10.1631/jzus.B2400576 Downloaded: 63 Clicked: 86 Cited: 0 Commented: 0(p.) <Full Text>

Constructing a PANoptosis-based prognostic signature to evaluate the immune landscape and therapy response in clear cell renal cell carcinoma

Yu DONG1, Zitong YANG1, Zhinan XIA1,2, Jiahao LIAO1, Zhiming CUI<3/sup>, Shenhao XU1, Bing LIU1, Liangliang REN1, Tengda WANG4, Wei GUO1, Shuwen WANG1, Yuyong WANG5,6, Cheng ZHANG1

DOI: 10.1631/jzus.B2400132 Downloaded: 330 Clicked: 291 Cited: 0 Commented: 0(p.) <Full Text>

Drug-assisted synthesis of copper nanoparticles and their induction of cuproptosis and necrosis for breast-cancer therapy

Yuewen WANG1, Jingjie GAO1, Yuying CHENG1, Hanling PAN1, Hanxiao TANG2, Chenguang LIU1

DOI: 10.1631/jzus.B2400163 Downloaded: 237 Clicked: 303 Cited: 0 Commented: 0(p.) <Full Text>

Potential relationship between circulating gene expression of ACE2, TLR4, and Il-17 and disease severity and out-come of COVID-19 hospitalized patients

Marwa A. DAHPY1,2, Ragaa H. SALAMA1, Abdel Raheim M.A. MEKI1,3, Ashraf Zein El-ABEDEEN4, Maiada K. HASHEM4, Ebtsam S. ABDULKAREEM5, Mohamed MOHANY6, Sinisa DJURASEVIC7, Amal N. IBRAHIM8, Nourhan M. HUSSEIN8 , Shima Gafar MANSOR9, Mohamed Ramadan IZZALDIN10, Marwa K. KHAIRALLAH11, Suzan Eid Elshishtawy IBRAHIM12, Alzahra ABDELBADEA13, Islam Khaled ali HARBY14, Fatma Y.A.ABBAS15, Rasha M. ALI15, Marwa A. SABET16, Salwa Seif ElDIN17, Abdelraouf M.S. ABDELRAOUF18, Amira A. KAMEL1

DOI: 10.1631/jzus.B2400345 Downloaded: 388 Clicked: 375 Cited: 0 Commented: 0(p.) <Full Text>

Improvement of neutral protease activity of Bacillus amyloliquefaciens LX-6 by combined ribosome engineering and medium optimization and its application in soybean meal fermentation

Yifan ZHU1*, Xinyi HUANG1*, Tao HAN2, Jiteng WANG2, Xiaoping YU1, Zheng MA1

DOI: 10.1631/jzus.B2400477 Downloaded: 388 Clicked: 224 Cited: 0 Commented: 0(p.) <Full Text>

Polarizing macrophages derived from human THP-1 cells in vitro: methods and protocols

Pengfei LI1,2, Lin CHEN3, Wei YUAN1, Xingqiang LI2, Xuesong FENG1,2

DOI: 10.1631/jzus.B2400516 Downloaded: 330 Clicked: 257 Cited: 0 Commented: 0(p.) <Full Text>

Acinetobacter sp. ME1: A Multifunctional Bacterium for Phytoremediation Utilizing Melanin Production, Heavy Metal Tolerance and Plant Growth Promotion

Soo Yeon LEE1, Kyung-Suk CHO1

DOI: 10.1631/jzus.B2400522 Downloaded: 349 Clicked: 300 Cited: 0 Commented: 0(p.) <Full Text>

Commensal bacteria play a fundamental role in maintaining gut immune homeostasis

Shuyu TU1, Yanan ZHANG2, Li ZHANG1 , Shu Jeffrey ZHU2

DOI: 10.1631/jzus.B2400431 Downloaded: 334 Clicked: 286 Cited: 0 Commented: 0(p.) <Full Text>

Consideration of culture in interpersonal psychotherapy practice in Asia: a case study

Xiaoyi ZHOU1,2, Haoyang ZHAO1,2, Guoxun FENG1,3, Jianbo HU1,2, Sarah E. BLEDSOE4, Manli HUANG1,2

DOI: 10.1631/jzus.B2400176 Downloaded: 150 Clicked: 159 Cited: 0 Commented: 0(p.) <Full Text>

Depleting CBR1 increases chemosensitivity by reducing stemness and quiescence traits in non-small-cell lung cancer

Weiwen LI1,2, Jialu ZhAO2, Weihong LAN2, Xiaofei YE2, Kejing YING1

DOI: 10.1631/jzus.B2400509 Downloaded: 96 Clicked: 151 Cited: 0 Commented: 0(p.) <Full Text>

Neuroscientific therapies for subjective tinnitus

Peng LIU1, Xinmiao XUE2, Zhixin ZHANG2, Hanwen ZHOU2, Cong XU1, Lijun ZHANG1, Zhen LI1, Yongqing ZHOU1, Shanwei SONG3, Yameng TIAN1, Fangyuan WANG2, Xiaoming LI1, Shiming YANG2

DOI: 10.1631/jzus.B2400579 Downloaded: 81 Clicked: 105 Cited: 0 Commented: 0(p.) <Full Text>

Effect of nitrate-to-ammonium ratio on changes in pakchoi folate constituents and contents in nutrient solution under hydroponic conditions

Yongcong ZHU1, Wei CHENG1, Yuemin NI2, Wuzhong NI1

DOI: 10.1631/jzus.B2500011 Downloaded: 83 Clicked: 150 Cited: 0 Commented: 0(p.) <Full Text>

Seeing the macro in the micro: a diffusion model-based approach for style transfer in cellular images

Jiayi CAI1, Yong HE1, Feng LIU2, Byung-Ho KANG3, Xuping FENG1

DOI: 10.1631/jzus.B2500012 Downloaded: 69 Clicked: 102 Cited: 0 Commented: 0(p.) <Full Text>

Early albumin infusion and mortality in elderly patients with sepsis based on analysis of MIMIC-IV database

Jinmin CHEN1, Yuanqiang LU2

DOI: 10.1631/jzus.B2400268 Downloaded: 74 Clicked: 104 Cited: 0 Commented: 0(p.) <Full Text>

Metagenomic sequencing reveals high reproducibility of human donor microbiota transplanted into germ-free mice via lower gut route

Yapeng YANG1,2,3, Xiang TAN2, Zeyue ZHANG2, Lifeng LIANG4, Zhifeng WU2, Jinhui HE2, Yuqing WANG2,3, Miaomiao DONG2, Jixia ZHENG2, Hang ZHANG2,5, Shuaifei FENG2, Wei CHENG2, Bota CUI6, Hong WEI2,5, Qinjin LI1

DOI: 10.1631/jzus.B2400495 Downloaded: 55 Clicked: 95 Cited: 0 Commented: 0(p.) <Full Text>

Regenerative potential of Schneiderian membrane-derived mesenchymal stem cells in sinus floor elevation model and calvarial defect model

Yuxin ZHAO1, Jia WANG1, Dongqi YOU1, Yifan LU1, Mengfei YU1, Misi SI1

DOI: 10.1631/jzus.B2400611 Downloaded: 55 Clicked: 89 Cited: 0 Commented: 0(p.) <Full Text>

Role of the Wnt signaling pathway in cementum formation, cementum regeneration, and cementocyte function

Tiancheng LI1,2, Xinyi ZENG1, Shuxian YANG1, Lynda Faye BONEWALD3, Peipei DUAN1

DOI: 10.1631/jzus.B2400637 Downloaded: 46 Clicked: 95 Cited: 0 Commented: 0(p.) <Full Text>

Cell proliferation and differentiation during epidermis renewal

Kai LIU1,2, Kaidi REN3, Dengwen LI2, Yang YANG1

DOI: 10.1631/jzus.B2500085 Downloaded: 24 Clicked: 31 Cited: 0 Commented: 0(p.) <Full Text>

Biomolecular condensates in Hippo pathway regulation

Yangqing SHAO, Yitong ZHANG, Wenxuan ZHU, Huasong LU

DOI: 10.1631/jzus.B2500092 Downloaded: 29 Clicked: 31 Cited: 0 Commented: 0(p.) <Full Text>

Successful in situ 5-aminolevulinic acid photodynamic therapy (5-ALA PDT) in 53-year-old female presented with cutaneous squamous cell carcinoma

Limin LUO, Xiaoling JIANG, Jianjun QIAO, Hong FANG, Jun LI

DOI: 10.1631/jzus.B2400164 Downloaded: 333 Clicked: 273 Cited: 0 Commented: 0(p.) <Full Text>

How do mechanical forces impact macrophages in the processes of mechanosensing and mechanotransduction?

Dan YU, Chenlu XU, Jinpeng JIANG, Wenyi SHEN, Huiyong ZHU

DOI: 10.1631/jzus.B2400183 Downloaded: 375 Clicked: 297 Cited: 0 Commented: 0(p.) <Full Text>

Cellulose nanofibril matrix drives the dynamic formation of spheroids

Yi LU, Guo LI, Yeqiu LI, Yuan YAO

DOI: 10.1631/jzus.B23Z0003 Downloaded: 1021 Clicked: 1407 Cited: 0 Commented: 0(p.) <Full Text>

Mitochondria derived from hESC-MSCs alleviate inflammatory response in HGFs

Bicong GAO, Chenlu SHEN, Kejia LV, Xuehui LI, Yongting ZHANG, Fan SHI, Hongyan DIAO, Hua YAO

DOI: 10.1631/jzus.B2300928 Downloaded: 673 Clicked: 1118 Cited: 0 Commented: (p.) <Full Text>

Single-cell transcriptome analysis reveals abnormal angiogenesis and placentation by loss of imprinted glutaminyl-peptide cyclotransferase

DOI: 10.1631/jzus.B2400099 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Recent research advances in the biological function and molecular mechanism of methylmalonic acid

DOI: 10.1631/jzus.B2400202 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Epigenetic factors associated with peri-implantitis: a review

DOI: 10.1631/jzus.B2400032 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Preclinical models in the study of lymph node metastasis

DOI: 10.1631/jzus.B2400052 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Therapeutic effect of baicalein as an antiparasitic agent against Toxoplasma gondii in vitro and in vivo

DOI: 10.1631/jzus.B2400235 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Two-step internal/external polydopamine (Cu2+) modified bioceramic scaffolds enhance antibacterial and alveolar bone regeneration capability

DOI: 10.1631/jzus.B23Z0004 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Applications of bioactive peptides in cosmeceuticals: a review

DOI: 10.1631/jzus.B2400029 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Pharmacological inhibition of ENaC or NCX can attenuate hepatic ischemia-reperfusion injury exacerbated by hypernatremia

DOI: 10.1631/jzus.B2300825 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Mechanisms of ribosomopathy and phase separation-related ribosomopathy

DOI: 10.1631/jzus.B2300904 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

A practice guideline for therapeutic drug monitoring of mycophenolic acid for solid organ transplants

DOI: 10.1631/jzus.B2400069 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Endomitosis: a new cell fate in the cell cycle leading to polyploidy in megakaryocytes and hepatocytes

DOI: 10.1631/jzus.B2400127 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Role of try and amy in the feeding, digestion, growth and development of the Japanese medaka (Oryzias latipes): insight from a comparative gene knockout study

DOI: 10.1631/jzus.B2400246 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Epidemiology and pathogenesis of the link between rheumatoid arthritis and periodontitis

DOI: 10.1631/jzus.B2300519 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Fibroblast growth factors and endometrial decidualization: models, mechanisms and related pathologies

DOI: 10.1631/jzus.B2300830 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Alamandine inhibits pathological retinal neovascularization by targeting MrgD-mediated HIF-1α/VEGFA pathway

DOI: 10.1631/jzus.B2300862 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Competitive roles of SO/delta-nesting-mediated sleep disruption under acute methamphetamine exposure in monkeys

DOI: 10.1631/jzus.B2400048 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Roles of the Keap1/Nrf2 pathway and mitophagy in liver diseases

DOI: 10.1631/jzus.B2400053 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Role of Wnt ligands and receptors in oral squamous cell carcinoma

DOI: 10.1631/jzus.B2400251 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Rescuing lysosomal/autophagic defects via nanoapproach: implications for lysosomal/autophagic defect related diseases

DOI: 10.1631/jzus.B2400186 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Pediatric inflammatory bowel disease in mother-child pairs: clinical risk factors and gut microbiota characteristics

DOI: 10.1631/jzus.B2400330 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Real-world data and evidence: pioneering frontiers in precision oncology

DOI: 10.1631/jzus.B2400285 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

3D printing-assisted freeze-casting of processed pyritum-doped β-TCP biomimetic scaffold with angiogenesis and bone regeneration capability

DOI: 10.1631/jzus.B2400340 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Genomic insights into the diversity of rice cultivars developed in Heilongjiang Province of China

DOI: 10.1631/jzus.B2400339 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Unmet needs of patients with intravascular large B-cell lymphoma: Three case reports and a literature review

DOI: 10.1631/jzus.B2300941 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Metapangenomics reveals an increased proportion of an Escherichia coli-dominated enterotype in older Chinese people

DOI: 10.1631/jzus.B2400341 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

New character of cancer immunotherapy: trends in viral tumor immunotherapy with influenza virus-based approaches

DOI: 10.1631/jzus.B2400381 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

EGCG as a therapeutic agent: a systematic review of recent advances and challenges in nanocarrier strategies

DOI: 10.1631/jzus.B2400040 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Food-derived bioactive peptides: health benefits, structure-activity relationships, and translational prospects

DOI: 10.1631/jzus.B2400106 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Recent advances in antibody optimization based on deep learning methods

DOI: 10.1631/jzus.B2400387 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

NRF2 nuclear translocation and interaction with DUSP1 may regulate osteogenic differentiation of murine mandibular osteoblasts stimulated by Pg-LPS

DOI: 10.1631/jzus.B2400203 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Pig meniscus single-cell sequencing reveals highly active red zone chondrocyte populations involved in stemness maintenance and vascularization development

DOI: 10.1631/jzus.B2400388 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Potential role of FNDC5 in exercise-induced improvement of cognitive function

DOI: 10.1631/jzus.B2400016 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Emerging role of the metabolite succinate in bone-related diseases

DOI: 10.1631/jzus.B2400406 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Shuyu capsule improves oestrous cycle-dependent depressive-like behaviour in PMDD mice by increasing GABAergic neuronal activation and down-regulating GABAAR δ subunit expression in the dPAG region

DOI: 10.1631/jzus.B2400410 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

An integrative combination of gas-liquid-phase plasma 4 mutagenesis and high-throughput screening to enhance 5 eicosapentaenoic acid production by Schizochytrium sp.

DOI: 10.1631/jzus.B2400427 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

A case of cardiac arrest and spontaneous renal hemorrhage in a male patient with persistent eosinophilia: highlighting the importance of early diagnosis of eosinophilic granulomatosis with polyangiitis

DOI: 10.1631/jzus.B2300940 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Selective anastasis induction by bee venom in normal cells: a prom-ising strategy for breast cancer therapy with minimal impact on cell viability

DOI: 10.1631/jzus.B2400466 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

COMPERA 2.0 risk stratification in patients with severe aortic stenosis: implication for group 2 pulmonary hypertension

DOI: 10.1631/jzus.B2400057 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Future of PARP inhibitors in cancer treatment: overcoming resistance and enhancing efficacy with combination therapies

DOI: 10.1631/jzus.B2400146 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

PICK1 modulates proliferation and migration of gastric cancer cells via regulating TLR4

DOI: 10.1631/jzus.B2400167 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

Potential effect of endothelial progenitor cells on pentylenetetrazole-induced seizures in rats: an evaluation of relevant long noncoding RNAs

DOI: 10.1631/jzus.B2400242 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

A novel bacterial strain for the removal of ammonia nitrogen from wastewater: Pseudomonas oleovorans QS-7

DOI: 10.1631/jzus.B2400257 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

From 2D to 3D: transforming malignant bone tumor research with advanced culture models

DOI: 10.1631/jzus.B2400288 Downloaded: 0 Clicked: 0 Cited: 0 Commented: (p.) <Full Text>

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