Journal of Zhejiang University SCIENCE B 2007 Vol.8 No.9 P.609-611

http://doi.org/10.1631/jzus.2007.B0609


Brain metastases of melanoma—mechanisms of attack on their defence system by engineered stem cells in the microenvironment


Author(s):  DIMITROV Borislav D., ATANASSOVA Penka A., RACHKOVA Mariana I.

Affiliation(s):  1. BORDANI, Alzano Lombardo, Bergamo 24022, Italy more

Corresponding email(s):   bdd11@yahoo.com

Key Words:  Melanoma, Brain metastases, Neural stem/progenitor cells (NSPCs), Cytosine deaminase


DIMITROV Borislav D., ATANASSOVA Penka A., RACHKOVA Mariana I.. Brain metastases of melanoma—mechanisms of attack on their defence system by engineered stem cells in the microenvironment[J]. Journal of Zhejiang University Science B, 2007, 8(9): 609-611.

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doi="10.1631/jzus.2007.B0609"
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%A RACHKOVA Mariana I.
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%D 2007
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2007.B0609

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T1 - Brain metastases of melanoma—mechanisms of attack on their defence system by engineered stem cells in the microenvironment
A1 - DIMITROV Borislav D.
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J0 - Journal of Zhejiang University Science B
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PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.2007.B0609


Abstract: 
This report gives a better emphasis on the role of targeted effectors (e.g. a combination of 5-FC with CD-NSPCs as compared to the application of NSPCs alone) and how such delivery of pro-drug activating enzymes and other tumor-killing substances may overcome melanocytic defence system, interact with and promote the host defence and immune response modulations not only in melanoma but, potentially, in other highly-metastatic cancers.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference

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Full Text:   <3928>

CLC number: R74

On-line Access: 2024-08-27

Received: 2023-10-17

Revision Accepted: 2024-05-08

Crosschecked: 0000-00-00

Cited: 2

Clicked: 8924

Citations:  Bibtex RefMan EndNote GB/T7714

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