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Biomaterials and additive manufacturing: osteochondral scaffold innovation applied to osteoarthritis (BAMOS project)
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Mario Monzn. Biomaterials and additive manufacturing: osteochondral scaffold innovation applied to osteoarthritis (BAMOS project)[J]. Journal of Zhejiang University Science A, 2018, 19(4): 329-330.
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Abstract: Osteoarthritis (OA) is a degenerative joint disease, typified by a loss of quality of cartilage and changes in bone at the interface of a joint, resulting in pain, stiffness, and reduced mobility. “According to the World Health Organization, 40% of people over the age of 70 have OA. This joint disease affects around 0.4 billion people with patients in Europe accounting for up to 30%. The figure is set to increase with the ageing problem”. The BAMOS project particularly addresses the challenges in OA treatment by providing novel cost effective osteochondral scaffold technology for early intervention of OA to delay or avoid the joint replacement operations.
[1]Canadas RF, Pina S, Marques AP, et al., 2016. Chapter 7– cartilage and bone regeneration—how close are we to bedside? In: Translating Regenerative Medicine to the Clinic, Elsevier, London, p.89-106.
[2]Monzón M, Liu C, Ajami S, et al., 2018. Functionally graded additive manufacturing to achieve functionality specifications of osteochondral scaffolds. Bio-Design and Manufacturing, 1(1):69-75.
[3]Ondrésik M, Maia A, Fatima R, et al., 2017. Management of knee osteoarthritis. Current status and future trends. Biotechnology and Bioengineering, 114(4):717-739.
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